Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21662664 | 0.88 | ELANE (0.38) | ALDH1A1KDM4EHSD17B10LMNAELANE | |
| SCHEMBL2515529 | 0.87 | ELANE (0.37) | ALDH1A1KDM4EHSD17B10TSHRELANE | |
| SCHEMBL29450106 | 0.87 | ELANE (0.37) | ALDH1A1KDM4EHSD17B10TSHRELANE | |
| Hydrochloric Acid SCHEMBL29259039 | 0.86 | ELANE (0.36) | ALDH1A1KDM4ETSHRELANEACHE | |
| SCHEMBL21342598 | 0.86 | ELANE (0.36) | ALDH1A1KDM4EHSD17B10LMNAELANE | |
| SCHEMBL23832314 | 0.86 | ELANE (0.36) | ALDH1A1KDM4EHSD17B10LMNAELANE | |
| SCHEMBL18121368 | 0.86 | ELANE (0.36) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL30152011 | 0.86 | ELANE (0.36) | ALDH1A1KDM4EHSD17B10LMNAELANE | |
| SCHEMBL21662665 | 0.85 | ELANE (0.35) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL18121459 | 0.84 | ELANE (0.38) | ALDH1A1KDM4EHSD17B10TSHRELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200040015-A1 | PRODRUG COMPOSITIONS | THE JOHNS HOPKINS UNIVERSITY | 2020-02-06 | — | — | US | disclosed |
| US-20100173851-A1 | INHIBITORS OF SERINE PROTEASES, PARTICULARLY HCV NS3-NS4A PROTEASE | VERTEX PHARMACEUTICALS INCORPORATED | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200040015-A1 | PRODRUG COMPOSITIONS | ABCB1, TYMP, PNP | ALDH1A1 303/4885KDM4E 2649/4885HSD17B10 986/4885 |
| US-20100173851-A1 | INHIBITORS OF SERINE PROTEASES, PARTICULARLY HCV NS3-NS4A PROTEASE | SERPINB1, PRSS1, SPINT2 | ALDH1A1 2015/4885KDM4E 1073/4885HSD17B10 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.