SCHEMBL29450106

SCHEMBL29450106

CC(=O)Oc1cc(C)cc(C)c1C(C)(C)CC(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.37
CYP2C9 P11712 2/20 0.35
ALDH1A1 P00352 5/20 0.35
ACHE P22303 1/20 0.35
KDM4E B2RXH2 5/20 0.34
TSHR P16473 3/20 0.34
GAA P10253 2/20 0.34
RAB9A P51151 1/20 0.34
CFD P00746 2/20 0.34
HTT P42858 1/20 0.34
FABP4 P15090 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
TTR P02766 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C8 P10632 1/20 0.33
CHRM1 P11229 1/20 0.33
ADRA1A P35348 1/20 0.33
PPARG P37231 1/20 0.33
HTR2B P41595 1/20 0.33
PPARA Q07869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2515529 1.00 ELANE (0.37) ELANECYP2C9ALDH1A1ACHEKDM4E
Hydrochloric Acid SCHEMBL29259039 0.99 ELANE (0.36) ELANECYP2C9ALDH1A1ACHEKDM4E
SCHEMBL24326604 0.90 CYP2C9 (0.36) ELANECYP2C9ALDH1A1KDM4ETSHR
SCHEMBL21662664 0.90 ELANE (0.38) ELANECYP2C9ALDH1A1ACHEKDM4E
SCHEMBL18121368 0.87 ELANE (0.36) ELANECYP2C9ALDH1A1ACHEKDM4E
SCHEMBL21342598 0.87 ELANE (0.36) ELANECYP2C9ALDH1A1ACHEKDM4E
SCHEMBL23832314 0.87 ELANE (0.36) ELANECYP2C9ALDH1A1ACHEKDM4E
SCHEMBL13245289 0.87 ALDH1A1 (0.38) ELANECYP2C9ALDH1A1ACHEKDM4E
SCHEMBL18114101 0.87 ELANE (0.44) ELANECYP2C9ALDH1A1TSHRFABP4
SCHEMBL30152011 0.87 ELANE (0.36) ELANECYP2C9ALDH1A1ACHEKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070276-A Prodrugs of xanomeline, prodrugs of trospium chloride and methods of using the same 人类生物科学股份有限公司 2026-05-19 CN disclosed
CN-116457344-B Low molecular weight protein degradation agent and application thereof 凯普托尔治疗学股份有限公司 2026-05-12 CN disclosed
EP-4667477-A2 PRODRUGS OF PHOSPHONAMIDE NUCLEOTIDE ANALOGUES AND THEIR PHARMACEUTICAL USE Gilead Sciences, Inc. (US) 2025-12-24 EP disclosed
EP-4192474-B1 PRODRUGS OF PHOSPHONAMIDE NUCLEOTIDE ANALOGUES AND THEIR PHARMACEUTICAL USE GILEAD SCIENCES INC (US) 2025-09-10 EP disclosed
CN-118119389-A Prodrugs and derivatives of des-phosphate nupharicin and uses thereof 人类生物科学股份有限公司 2024-05-31 CN disclosed
CN-117956991-A N, N-dimethyltryptamine and related hallucinogens and uses thereof 人类生物科学股份有限公司 2024-04-30 CN disclosed
CN-117924313-A Tetrahydrothienopyridine derivative and preparation method and application thereof 仁合益康集团有限公司 2024-04-26 CN disclosed
CN-117897149-A 3, 4-methylenedioxymethamphetamine and related hallucinogens and uses thereof 人类生物科学股份有限公司 2024-04-16 CN disclosed
CN-117480153-A Azabicyclo [3.1.0] hexane compounds 大塚制药株式会社 2024-01-30 CN disclosed
WO-2023137453-A1 PRODRUGS OF 3,4-METHYLENEDIOXY-N-METHCATHINONE AND USES THEREOF TERRAN BIOSCIENCES INC. (US) 2023-07-20 WO disclosed
CN-116457344-A Low molecular weight protein degradation agent and application thereof 凯普托尔治疗学股份有限公司 2023-07-18 CN disclosed
WO-2023115002-A1 ANALOGS OF 4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE TERRAN BIOSCIENCES INC. (US) 2023-06-22 WO disclosed
EP-4192474-A1 PRODRUGS OF PHOSPHONAMIDE NUCLEOTIDE ANALOGUES AND THEIR PHARMACEUTICAL USE GILEAD SCIENCES, INC. (US) 2023-06-14 EP disclosed
EP-4188373-A1 LOW MOLECULAR WEIGHT PROTEIN DEGRADERS AND THEIR APPLICATIONS Captor Therapeutics S.A. (PL) 2023-06-07 EP disclosed
CN-116194144-A Prodrugs of phosphoramide nucleotide analogs and pharmaceutical uses thereof 吉利德科学公司 2023-05-30 CN disclosed
EP-4121437-A1 PRODRUGS OF 4'-C-SUBSTITUTED-2-HALO-2'-DEOXYADENOSINE NUCLEOSIDES AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2023-01-25 EP disclosed
WO-2022265020-A1 AZABICYCLO[3.1.0]HEXANE COMPOUND 大塚製薬株式会社 2022-12-22 WO disclosed
WO-2022029138-A1 LOW MOLECULAR WEIGHT PROTEIN DEGRADERS AND THEIR APPLICATIONS CAPTOR THERAPEUTICS S.A. (PL) 2022-02-10 WO disclosed