Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CFD | P00746 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450106 | 1.00 | ELANE (0.37) | ELANECYP2C9ALDH1A1ACHEKDM4E | |
| Hydrochloric Acid SCHEMBL29259039 | 0.99 | ELANE (0.36) | ELANECYP2C9ALDH1A1ACHEKDM4E | |
| SCHEMBL24326604 | 0.90 | CYP2C9 (0.36) | ELANECYP2C9ALDH1A1KDM4ETSHR | |
| SCHEMBL21662664 | 0.90 | ELANE (0.38) | ELANECYP2C9ALDH1A1ACHEKDM4E | |
| SCHEMBL18121368 | 0.87 | ELANE (0.36) | ELANECYP2C9ALDH1A1ACHEKDM4E | |
| SCHEMBL21342598 | 0.87 | ELANE (0.36) | ELANECYP2C9ALDH1A1ACHEKDM4E | |
| SCHEMBL23832314 | 0.87 | ELANE (0.36) | ELANECYP2C9ALDH1A1ACHEKDM4E | |
| SCHEMBL13245289 | 0.87 | ALDH1A1 (0.38) | ELANECYP2C9ALDH1A1ACHEKDM4E | |
| SCHEMBL18114101 | 0.87 | ELANE (0.44) | ELANECYP2C9ALDH1A1TSHRFABP4 | |
| SCHEMBL30152011 | 0.87 | ELANE (0.36) | ELANECYP2C9ALDH1A1ACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112789085-A | Compounds useful in HIV therapy | 葛兰素史克知识产权第二有限公司 | 2021-05-11 | — | — | CN | claimed |
| US-20260035371-A1 | COMPOUNDS USEFUL IN HIV THERAPY | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2026-02-05 | — | — | US | disclosed |
| US-12240853-B2 | Compounds useful in HIV therapy | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2025-03-04 | — | — | US | disclosed |
| US-20250049748-A1 | ANALOGS OF 4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE | TERRAN BIOSCIENCES INC (US) | 2025-02-13 | — | — | US | disclosed |
| EP-3277662-B1 | HYDROGEN SULFIDE PRECURSORS AND CONJUGATES THEREOF | UNIV GEORGIA STATE RES FOUND (US) | 2025-01-22 | — | — | EP | disclosed |
| US-20240286999-A1 | AZABICYCLO[3.1.0]HEXANE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-08-29 | — | — | US | disclosed |
| US-20240247024-A1 | INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE (NNMT) | UNIVERSITEIT LEIDEN (NL) | 2024-07-25 | — | — | US | disclosed |
| US-20240182473-A1 | COMPOUNDS USEFUL IN HIV THERAPY | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2024-06-06 | — | — | US | disclosed |
| CN-118119389-A | Prodrugs and derivatives of des-phosphate nupharicin and uses thereof | 人类生物科学股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-117956991-A | N, N-dimethyltryptamine and related hallucinogens and uses thereof | 人类生物科学股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| US-20090227541-A1 | oxaboroles such as 3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol, useful for treating bacterial infections; microbiocides; antibiotics | ANACOR PHARMACEUTICALS, INC. (US) | 2009-09-10 | — | — | US | disclosed |
| US-20090227541-A1 | oxaboroles such as 3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol, useful for treating bacterial infections; microbiocides; antibiotics | ANACOR PHARMACEUTICALS, INC. (US) | 2009-09-10 | — | — | US | disclosed |
| US-20090227541-A1 | oxaboroles such as 3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol, useful for treating bacterial infections; microbiocides; antibiotics | ANACOR PHARMACEUTICALS, INC. (US) | 2009-09-10 | — | — | US | disclosed |
| US-7534902-B2 | Fluorescence assays with improved sensitivity | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-05-19 | — | — | US | disclosed |
| US-7534902-B2 | Fluorescence assays with improved sensitivity | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-05-19 | — | — | US | disclosed |
| US-7534902-B2 | Fluorescence assays with improved sensitivity | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-05-19 | — | — | US | disclosed |
| WO-2008157726-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008157726-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |
| US-20050147997-A1 | Fluorescence assays with improved sensitivity | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2005-07-07 | — | — | US | disclosed |
| WO-2005047245-A2 | FLUORESCENCE ASSAYS WITH IMPROVED BLOCKING GROUPS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2005-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050147997-A1 | Fluorescence assays with improved sensitivity | UACA, HNRNPUL1, FUS | ELANE 524/4885CYP2C9 4779/4885ALDH1A1 3668/4885 |
| US-20240247024-A1 | INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE (NNMT) | NNMT, NAMPT, NNT | ELANE 3082/4885CYP2C9 1411/4885ALDH1A1 629/4885 |
| US-20260035371-A1 | COMPOUNDS USEFUL IN HIV THERAPY | CCR5, CCR1, CYC1 | ELANE 565/4885CYP2C9 304/4885ALDH1A1 1180/4885 |
| US-20250049748-A1 | ANALOGS OF 4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE | PNMT, HNMT, COMT | ELANE 2180/4885CYP2C9 1054/4885ALDH1A1 904/4885 |
| US-20240182473-A1 | COMPOUNDS USEFUL IN HIV THERAPY | CD4, CCR5, G6PD | ELANE 82/4885CYP2C9 845/4885ALDH1A1 398/4885 |
| US-20240286999-A1 | AZABICYCLO[3.1.0]HEXANE COMPOUND | MALT1, CXCR1, AZI2 | ELANE 3035/4885CYP2C9 450/4885ALDH1A1 479/4885 |
| US-20090227541-A1 | oxaboroles such as 3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol, useful for treating bacterial infections; microbiocides; antibiotics | OXA1L, TLR1, OXER1 | ELANE 12/4885CYP2C9 1816/4885ALDH1A1 646/4885 |
| US-12240853-B2 | Compounds useful in HIV therapy | CCR5, CD4, LSS | ELANE 38/4885CYP2C9 745/4885ALDH1A1 678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.