SCHEMBL1324529

SCHEMBL1324529

PC(C1CCCCC1)C1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.48
SHBG P04278 1/20 0.48
TP53 P04637 2/20 0.43
KDM4E B2RXH2 2/20 0.42
LMNA P02545 2/20 0.42
GMNN O75496 1/20 0.42
MAPT P10636 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 3/20 0.37
HSD17B10 Q99714 1/20 0.37
CYP2D6 P10635 2/20 0.36
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
TSHR P16473 1/20 0.36
KMT2A Q03164 1/20 0.36
MLNR O43193 1/20 0.36
ABCB11 O95342 1/20 0.36
EGFR P00533 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1337312 0.96 EPHX1 (0.43) EPHX1SHBGTP53KDM4ELMNA
SCHEMBL8098756 0.79
SCHEMBL14302100 0.74 SHBG (0.56) EPHX1SHBGTP53KDM4ELMNA
SCHEMBL20461099 0.73
SCHEMBL196915 0.72 EPHX1 (0.37) EPHX1SHBGTP53LMNAALDH1A1
SCHEMBL3959481 0.71 EPHX1 (0.36) EPHX1SHBGTP53KDM4ELMNA
SCHEMBL1323089 0.71 EPHX1 (0.55) EPHX1SHBGTP53KDM4ELMNA
Hydrochloric Acid SCHEMBL29207955 0.71 SHBG (0.42) EPHX1SHBGTP53KDM4ELMNA
SCHEMBL1317994 0.69 EPHX1 (0.45) EPHX1SHBGTP53KDM4ELMNA
SCHEMBL3231723 0.69 EPHX1 (0.45) EPHX1SHBGTP53KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1502605-B Preparation of polyisocyanates containing uretidione groups BAYER AG 2010-10-13 CN claimed
US-7067654-B2 Preparation of polyisocyanates containing uretdione groups BAYER MATERIALSCIENCE AG (DE) 2006-06-27 US claimed
US-20040110915-A1 for production of polyurethanes via catalytic polymerization with trimethylphosphine; improved storage stability BAYER AKTIENGESELLSCHAFT (DE) 2004-06-10 US claimed
CN-1502605-A Prepartion of polyisocyanates containing uretdione groups 2004-06-09 CN claimed
US-20040106789-A1 Preparation of polyisocyanates containing uretdione groups COVESTRO DEUTSCHLAND AG (DE) 2004-06-03 US claimed
US-12534590-B2 Recycle content cyclobutane diol polyester EASTMAN CHEMICAL COMPANY (US) 2026-01-27 US disclosed
US-12492281-B2 Polyisocyanurate materials as electrical potting compounds COVESTRO DEUTSCHLAND AG (DE) 2025-12-09 US disclosed
EP-4004081-B1 RECYCLE CONTENT CYCLOBUTANE DIOL POLYESTER EASTMAN CHEM CO (US) 2025-09-17 EP disclosed
US-20250276949-A1 RECYCLE CONTENT (C4)ALKANAL EASTMAN CHEMICAL COMPANY (US) 2025-09-04 US disclosed
US-12338211-B2 Recycle content (C4)alkanal EASTMAN CHEMICAL COMPANY (US) 2025-06-24 US disclosed
CN-119912669-A Cyclic butanediol polyester as recovered component 伊士曼化工公司 2025-05-02 CN disclosed
CN-114174375-B Cyclic butanediol polyester as recovered component 伊士曼化工公司 2025-01-28 CN disclosed
US-4866188-A CYCLODEHYDRATING POLYHYDROXY COMPOUND WITH RUTHENIUM HALIDE CATALYST NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1989-09-12 US disclosed
US-4595701-A Reacting carbon monoxide and hydrogen in liquid phase in the presence of a rhodium and trialkylphosphine catalyst AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1986-06-17 US disclosed
EP-0095348-B1 HIGH MOLECULAR WEIGHT POLYBENZIMIDAZOLES CELANESE CORPORATION (US) 1986-04-09 EP disclosed
US-4483977-A TETRAMINOBIPHENYL AND ISOPHTHALIC ACID CELANESE CORPORATION (US) 1984-11-20 US disclosed
US-4452967-A MELT POLYMERIZATION OF AROMATIC CARBOXY DIAMINE CELANESE CORPORATION (US) 1984-06-05 US disclosed
EP-0095348-A2 High molecular weight polybenzimidazoles CELANESE CORPORATION (US) 1983-11-30 EP disclosed
US-4414383-A High molecular weight polybenzimidazole preparation with phosphorus containing polymerization catalyst CELANESE CORPORATION (US) 1983-11-08 US disclosed
US-4267384-A FORMALDEHYDE, CARBON MONOXIDE, AND HYDROGEN REACTANTS USING A RUTHENIUM-HALOGEN-COMPLEX AS HYDROGENATION CATALYST NATIONAL DISTILLERS AND CHEMICAL CORP. (US) 1981-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534590-B2 Recycle content cyclobutane diol polyester PGD, MCCC2, PCCA EPHX1 2307/4885SHBG 3064/4885TP53 4370/4885
US-20040106789-A1 Preparation of polyisocyanates containing uretdione groups UROD, PUF60, UTS2R EPHX1 4093/4885SHBG 512/4885TP53 4468/4885
US-12338211-B2 Recycle content (C4)alkanal ALKBH3, AKR1C4, CBR1 EPHX1 21/4885SHBG 3909/4885TP53 3837/4885
US-20250276949-A1 RECYCLE CONTENT (C4)ALKANAL ALKBH3, AKR1C4, CBR1 EPHX1 21/4885SHBG 3909/4885TP53 3837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.