Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474924 | 0.81 | TYMP (0.59) | TYMPMAPK1HPGDTK1 | |
| SCHEMBL12400915 | 0.81 | TYMP (0.59) | TYMPMAPK1HPGDTK1 | |
| SCHEMBL21936363 | 0.79 | TYMP (0.55) | TYMPMAPK1TK1 | |
| Triphosphate SCHEMBL10474883 | 0.79 | TYMP (0.58) | TYMPMAPK1HPGDTK1 | |
| SCHEMBL4094686 | 0.76 | TYMP (0.63) | TYMPMAPK1HPGD | |
| SCHEMBL14271995 | 0.74 | P2RY6 (0.43) | — | |
| SCHEMBL16102563 | 0.72 | TYMP (0.58) | TYMPMAPK1HPGD | |
| SCHEMBL8905174 | 0.71 | TYMP (0.52) | TYMPMAPK1HPGDTK1 | |
| SCHEMBL10474814 | 0.71 | TYMP (0.56) | TYMPMAPK1HPGDTK1 | |
| SCHEMBL10474817 | 0.70 | TYMP (0.56) | TYMPMAPK1HPGDTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7777013-B2 | Labeled nucleotide analogs and uses therefor | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-20090018324-A1 | LABELED NUCLEOTIDE ANALOGS AND USES THEREFOR | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018324-A1 | LABELED NUCLEOTIDE ANALOGS AND USES THEREFOR | POLRMT, DNTT, NUDT1 | TYMP 5/4885MAPK1 4057/4885HPGD 948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.