Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713764 | 0.81 | TYMP (0.67) | TYMPMAPK1HPGD | |
| SCHEMBL8711443 | 0.77 | TYMP (0.51) | TYMPMAPK1HPGDTK1 | |
| SCHEMBL8882781 | 0.75 | SLC9A1 (0.38) | TYMP | |
| SCHEMBL7219926 | 0.73 | MAPK1 (0.54) | TYMPMAPK1HPGDTK1 | |
| Triphosphate SCHEMBL10474883 | 0.72 | TYMP (0.58) | TYMPMAPK1HPGDTK1 | |
| SCHEMBL8711439 | 0.72 | TYMP (0.48) | TYMPMAPK1HPGDTK1 | |
| SCHEMBL13245382 | 0.71 | TYMP (0.51) | TYMPMAPK1HPGDTK1 | |
| SCHEMBL16382269 | 0.70 | MAPK1 (0.51) | TYMPMAPK1HPGDTK1 | |
| SCHEMBL12400915 | 0.70 | TYMP (0.59) | TYMPMAPK1HPGDTK1 | |
| SCHEMBL10474924 | 0.70 | TYMP (0.59) | TYMPMAPK1HPGDTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398231-B1 | Nucleoside analogs | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 1997-07-16 | — | — | EP | disclosed |
| EP-0398231-A2 | Nucleoside analogs | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1990-11-22 | — | — | EP | disclosed |