SCHEMBL1324797

SCHEMBL1324797

CCCC(Oc1ccnc(C)c1C(=O)O)C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MMP13 P45452 7/20 0.41
▸ GPR119 Q8TDV5 7/20 0.41
▸ DPP4 P27487 1/20 0.41
▸ USP30 Q70CQ3 1/20 0.40
▸ FAAH O00519 1/20 0.39
▸ MMP1 P03956 1/20 0.39
▸ PDE4D Q08499 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1324799 0.78 GPR119 (0.49) MMP13GPR119DPP4USP30
SCHEMBL2675436 0.72 GPR119 (0.45) MMP13GPR119
SCHEMBL4114220 0.71 GPR119 (0.53) GPR119PDE4D
SCHEMBL31663264 0.70 PTPN2 (0.49) GPR119FAAH
SCHEMBL23672116 0.69 GPR119 (0.42) MMP13GPR119DPP4FAAH
SCHEMBL586400 0.67 SSTR4 (0.40) GPR119USP30PDE4D
SCHEMBL19286080 0.67 GPR119 (0.54) GPR119DPP4PDE4D
SCHEMBL1295933 0.67 GPR119 (0.48) MMP13GPR119DPP4
SCHEMBL7871971 0.66 GPR119 (0.57) GPR119DPP4
SCHEMBL7871972 0.66 GPR119 (0.57) GPR119DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110269734-A1 PIPERIDINYL GPCR AGONISTS PROSIDION LIMITED (GB) 2011-11-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269734-A1 PIPERIDINYL GPCR AGONISTS GPR119, GPR27, GLP1R MMP13 3624/4885GPR119 1/4885DPP4 410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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