Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | PAM | P19021 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427938 | 1.00 | HTR6 (0.44) | HTR6ALDH1A1MAPTPOLBHPGD | |
| SCHEMBL132480 | 0.86 | HTR6 (0.51) | HTR6HTR2AKDM4ESIGMAR1 | |
| SCHEMBL7762670 | 0.86 | HTR6 (0.51) | HTR6HTR2AKDM4ESIGMAR1 | |
| SCHEMBL27516985 | 0.85 | ALDH1A1 (0.35) | HTR6ALDH1A1MAPTPOLBHPGD | |
| SCHEMBL11576712 | 0.79 | HTR6 (0.50) | HTR6HTR2AKDM4ESIGMAR1 | |
| SCHEMBL11414399 | 0.79 | HTR6 (0.46) | HTR6HTR2AKDM4ESIGMAR1 | |
| SCHEMBL11575785 | 0.75 | HTR6 (0.43) | HTR6HTR2ASIGMAR1 | |
| SCHEMBL1779074 | 0.75 | HTR6 (0.49) | HTR6HTR2AKDM4ESIGMAR1 | |
| SCHEMBL629578 | 0.75 | HTR6 (0.49) | HTR6HTR2AKDM4ESIGMAR1 | |
| SCHEMBL292407 | 0.75 | HTR6 (0.49) | HTR6HTR2AKDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912311-A | Olefin polymerization method comprising allyl-cycloalkadienyl dianions as catalyst precursors | UNIVATION TECHNOLOGIES, LLC | 1999-06-15 | — | — | US | disclosed |
| US-5866497-A | Catalyst for the production of olefin polymers | UNIVATION TECHNOLOGIES LLC (US) | 1999-02-02 | — | — | US | disclosed |
| US-5700748-A | Catalyst for the production of olefin polymers comprising a bridging allyl-cyclodienyl ligand on a metal atom | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-12-23 | — | — | US | disclosed |
| CN-1157291-A | Catalyst for production of olefin polymers | UNION CARBIDE CHEM PLASTIC (US) | 1997-08-20 | — | — | CN | disclosed |
| EP-0771777-A1 | Catalyst precursor for the production of olefin polymers | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-05-07 | — | — | EP | disclosed |