Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681981 | 0.79 | GABRA1 (0.58) | GABRA1GABRB2GABRG2GABRB3PDCD1 | |
| SCHEMBL14551465 | 0.78 | GABRA1 (0.83) | GABRA1GABRB2GABRG2GABRB3PDCD1 | |
| SCHEMBL487534 | 0.78 | GABRA1 (0.57) | GABRA1GABRB2GABRG2GABRB3PDCD1 | |
| SCHEMBL10331780 | 0.78 | GABRA1 (0.42) | GABRA1GABRB2GABRG2GABRB3PDCD1 | |
| SCHEMBL15371488 | 0.76 | GABRA1 (0.41) | GABRA1GABRB2GABRG2GABRB3PDCD1 | |
| SCHEMBL22380007 | 0.76 | GABRA1 (0.41) | GABRA1GABRB2GABRG2GABRB3PDCD1 | |
| SCHEMBL14485064 | 0.76 | GABRA1 (0.50) | GABRA1GABRB2SLC6A2CYP2D6SLC6A4 | |
| Hydrogen Peroxide SCHEMBL10512587 | 0.76 | GABRA1 (0.55) | GABRA1GABRB2GABRG2GABRB3PDCD1 | |
| SCHEMBL14485067 | 0.76 | GABRA1 (0.50) | GABRA1GABRB2SLC6A2CYP2D6SLC6A4 | |
| SCHEMBL14485548 | 0.74 | GABRA1 (0.48) | GABRA1GABRB2CDK4CCND1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767657-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2010-08-03 | — | — | US | disclosed |
| US-20070155699-A1 | Boron-containing small molecules | ANACOR PHARMACEUTICALS (US) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155699-A1 | Boron-containing small molecules | ETF1, POLR1C, DPM1 | GABRA1 1910/4885GABRB2 1120/4885GABRG2 2059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.