Sugi Predict

Sugi Predict / Compounds / SCHEMBL6681981

SCHEMBL6681981

SCHEMBL6681981

CC(C)Cc1ccccc1CO

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GABRA1 P14867 3/20 0.58
▸ GABRB2 P47870 2/20 0.58
▸ APOBEC3G Q9HC16 1/20 0.43
▸ CYP2D6 P10635 2/20 0.42
▸ SLC6A2 P23975 1/20 0.42
▸ SLC6A4 P31645 1/20 0.42
▸ SLC6A3 Q01959 1/20 0.42
▸ KCNH2 Q12809 1/20 0.42
▸ PDCD1 Q15116 1/20 0.41
▸ CD274 Q9NZQ7 1/20 0.41
▸ CYP4F2 P78329 2/20 0.39
▸ CYP4A11 Q02928 2/20 0.39
▸ TRPA1 O75762 1/20 0.39
▸ GABRG2 P18507 1/20 0.37
▸ GABRB3 P28472 1/20 0.37
▸ KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Peroxide SCHEMBL5685702 0.87 GABRA1 (0.65) GABRA1GABRB2CYP2D6SLC6A2SLC6A4
SCHEMBL840750 0.87 GABRA1 (0.64) GABRA1GABRB2CYP2D6SLC6A2SLC6A4
SCHEMBL5174936 0.85 GABRA1 (0.61) GABRA1GABRB2CYP2D6SLC6A2SLC6A4
SCHEMBL5174943 0.85 GABRA1 (0.61) GABRA1GABRB2CYP2D6SLC6A2SLC6A4
SCHEMBL1129263 0.84 CYP2D6 (0.41) GABRA1GABRB2APOBEC3GCYP2D6SLC6A2
SCHEMBL11317155 0.83 GABRA1 (0.60) GABRA1GABRB2SLC6A2SLC6A4SLC6A3
SCHEMBL27894267 0.82 SLC6A2 (0.50) CYP2D6SLC6A2SLC6A4SLC6A3KMT2A
SCHEMBL10525253 0.82 GABRA1 (0.54) GABRA1GABRB2SLC6A2SLC6A4SLC6A3
Bicarbonate SCHEMBL27568192 0.81 GABRA1 (0.58) GABRA1GABRB2KMT2A
SCHEMBL14551465 0.80 GABRA1 (0.83) GABRA1GABRB2APOBEC3GSLC6A2PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119233765-A Biodegradable microcapsule and preparation method thereof 赞普拉有限公司 2024-12-31 — — CN disclosed
US-20230339937-A1 CONDENSED RING COMPOUNDS THAT INHIBIT H-PGDS SATO PHARMACEUTICAL CO., LTD. (JP) 2023-10-26 — — US disclosed
US-20230339937-A1 CONDENSED RING COMPOUNDS THAT INHIBIT H-PGDS SATO PHARMACEUTICAL CO., LTD. (JP) 2023-10-26 — — US disclosed
CN-113549008-B Diamine monomer containing aryl substituted pyridine structure, preparation and application thereof, teleger base polymer, preparation and application thereof 吉林大学 2023-02-24 — — CN disclosed
WO-2021256569-A1 CONDENSED RING COMPOUNDS THAT INHIBIT H-PGDS 佐藤製薬株式会社 2021-12-23 — — WO disclosed
CN-113549008-A Diamine monomer containing aryl substituted pyridine structure, preparation and application thereof, Teleger base polymer, preparation and application thereof 吉林大学 2021-10-26 — — CN disclosed
US-9579325-B2 Modulators of TNF-α signaling GENZYME CORPORATION (US) 2017-02-28 — — US disclosed
US-9200319-B2 Nucleotides and nucleosides and methods for their use in DNA sequencing LASERGEN, INC. (US) 2015-12-01 — — US disclosed
US-20150140559-A1 NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING LASERGEN, INC. (US) 2015-05-21 — — US disclosed
US-20150126512-A1 Modulators Of TNF-Alpha Signaling GENZYME CORPORATION (US) 2015-05-07 — — US disclosed
US-8877905-B2 Nucleotides and nucleosides and methods for their use in DNA sequencing LASERGEN, INC. (US) 2014-11-04 — — US disclosed
US-20140051848-A1 NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING AGILENT TECHNOLOGIES, INC. 2014-02-20 — — US disclosed
US-20130310388-A1 Modulators of TNF-Alpha Signaling GENZYME CORPORATION (US) 2013-11-21 — — US disclosed
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 — — EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 — — US disclosed
US-5149884-A Oxidative dehydrogenation of aromatic or aliphatic alcohols in gas phase BASF AKTIENGESELLSCHAFT (DE) 1992-09-22 — — US disclosed
EP-0244632-B1 TUBE BUNDLE REACTOR, ITS USE IN EXOTHERMAL ORGANIC REACTIONS AND PROCESS FOR THE PREPARATION OF KETONES AND ALDEHYDES BASF Aktiengesellschaft (DE) 1991-02-20 — — EP disclosed
EP-0244632-A2 Tube bundle reactor, its use in exothermal organic reactions and process for the preparation of ketones and aldehydes BASF Aktiengesellschaft (DE) 1987-11-11 — — EP disclosed
US-4224254-A OXIDATION OF AROMATIC ALCOHOLS, SILVER CATALYST BASF AKTIENGESELLSCHAFT (DE) 1980-09-23 — — US disclosed
EP-0004881-A2 Process for the preparation of aromatic and araliphatic aldehydes BASF Aktiengesellschaft (DE) 1979-10-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150126512-A1 Modulators Of TNF-Alpha Signaling TNF, TNFRSF1A, TNFRSF9 GABRA1 1264/4885GABRB2 1057/4885APOBEC3G 4739/4885
US-20230339937-A1 CONDENSED RING COMPOUNDS THAT INHIBIT H-PGDS HPGDS, PTGS1, PTGIS GABRA1 3423/4885GABRB2 3822/4885APOBEC3G 3530/4885
US-20130310388-A1 Modulators of TNF-Alpha Signaling TNF, TNFRSF1A, TNFRSF9 GABRA1 1264/4885GABRB2 1057/4885APOBEC3G 4739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.