Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 4/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 4/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14114732 | 0.79 | S1PR1 (0.39) | PTPN7DUSP3NR3C2 | |
| SCHEMBL86405 | 0.78 | RXRA (0.49) | ARSLC6A4 | |
| SCHEMBL13437653 | 0.77 | KDM4E (0.43) | CYP2D6CYP2C9CYP2C19NPSR1 | |
| SCHEMBL26738659 | 0.77 | ACHE (0.38) | PTPN7DUSP3SLC6A4 | |
| SCHEMBL5018562 | 0.74 | ALDH1A1 (0.48) | KIF11 | |
| SCHEMBL12835009 | 0.73 | ACHE (0.38) | DRD4NPSR1 | |
| SCHEMBL11949141 | 0.73 | PTPRB (0.35) | ARSLC6A4KIF11 | |
| SCHEMBL13567934 | 0.73 | PPARG (0.38) | DRD4SLC6A4L3MBTL1 | |
| SCHEMBL4797160 | 0.73 | TAAR1 (0.50) | CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL2642102 | 0.73 | AR (0.48) | PTPN7DUSP3ARVNN1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179137-A1 | PYRIDONE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179137-A1 | PYRIDONE COMPOUND | PTGER4, P2RY4, PTGER1 | PTPN7 1372/4885DUSP3 3345/4885AR 721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.