SCHEMBL1325

SCHEMBL1325

O=C(n1ccnc1)n1ccnc1

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.45
MGLL Q99685 3/20 0.45
ALDH1A1 P00352 2/20 0.43
LMNA P02545 1/20 0.41
EGLN3 Q9H6Z9 1/20 0.40
MAPT P10636 1/20 0.39
NFKB1 P19838 1/20 0.38
QPCT Q16769 1/20 0.38
HSD17B10 Q99714 1/20 0.38
QPCTL Q9NXS2 1/20 0.38
CYP19A1 P11511 2/20 0.36
TBXAS1 P24557 2/20 0.35
CYP3A4 P08684 1/20 0.35
BAZ2B Q9UIF8 1/20 0.35
CYP24A1 Q07973 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15846673 1.00 FAAH (0.45) FAAHMGLLALDH1A1LMNAEGLN3
Hydrogen Sulfide SCHEMBL10814521 0.97 FAAH (0.44) FAAHMGLLALDH1A1LMNAEGLN3
Hydrochloric Acid SCHEMBL6226784 0.97 FAAH (0.44) FAAHMGLLALDH1A1LMNAEGLN3
SCHEMBL10814524 0.97 FAAH (0.44) FAAHMGLLALDH1A1LMNAEGLN3
Phosphine SCHEMBL31680518 0.97 FAAH (0.44) FAAHMGLLALDH1A1LMNAEGLN3
SCHEMBL2194853 0.97 FAAH (0.44) FAAHMGLLALDH1A1LMNAEGLN3
Methylene Chloride SCHEMBL4130957 0.91 ALDH1A1 (0.42) FAAHMGLLALDH1A1LMNAEGLN3
SCHEMBL2610160 0.91 FAAH (0.41) FAAHMGLLALDH1A1LMNAEGLN3
SCHEMBL7736262 0.91 FAAH (0.44) FAAHMGLLALDH1A1LMNAEGLN3
SCHEMBL618874 0.89 ALDH1A1 (0.43) FAAHMGLLALDH1A1LMNAEGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 118981 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637702-B2 Process for preparing substituted imidazo[1,5-α]pyrazines HOFFMANN-LA ROCHE INC. (US) 2026-05-26 US claimed
US-12637469-B2 1H-pyrazole derivative and application thereof as dual target inhibitor of Syk and VEGFR2 OCUMENSION THERAPEUTICS (SUZHOU) CO., LTD. (CN) 2026-05-26 US claimed
CN-122080119-A Synthesis method of MC-Gly-Gly-Phe-Gly tetrapeptide linker 2026-05-26 CN claimed
CN-122079809-A Synthesis method of dipeptide linker of antibody coupling degradation agent 2026-05-26 CN claimed
CN-119800543-B Preparation process of antibacterial acrylic fabric Jiangsu Yimolecular Textile Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122075719-A Neuraminidase-ROS dual-response nano-carrier as well as preparation method and application thereof 2026-05-26 CN claimed
CN-122079954-A Synthesis method of benzo [1,3] oxathia-2-one 2026-05-26 CN claimed
CN-122094701-A TLR3 binding bicyclic peptide ligands 2026-05-26 CN claimed
CN-122094944-A Preparation of oxadiazolyl amino benzobises method for preparing azepine derivatives 2026-05-26 CN claimed
CN-122071449-A Substituted biphenyl compounds and application thereof in synthesis of cola pyrroside 北京凯因格领生物技术有限公司 2026-05-22 CN claimed
US-4189583-A FROM 1-METHYL-2-OXO-3-METHYLENE-4-(3'-METHOXYPHENYL)-4 -(CARBOXYMETHYLENE)PIPERIDINE BY CYCLIZATION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1980-02-19 US claimed
EP-0006931-A1 NEW SUBSTITUTED BY-PRODUCTS OF 1,3-DIHYDRO IMIDAZO (4,5-b) PYRIDIN-2-ONE, PROCESS, APPLICATION, COMPOSITIONS AND INTERMEDIATE COMPOUNDS OBTAINED ROUSSEL-UCLAF (FR) 1980-01-23 EP claimed
EP-0004358-A1 N-oxacyclylalkyl piperidines, process for their preparation, pharmaceutical compositions containing these compounds CIBA-GEIGY AG (CH) 1979-10-03 EP claimed
WO-1979000206-A1 NEW SUBSTITUTED BY-PRODUCTS OF 1,3-DIHYDRO IMIDAZO(4,5-B)PYRIDIN-2-ONE,PROCESS,APPLICATION,COMPOSITIONS AND INTERMEDIATE COMPOUNDS OBTAINED ROUSSEL UCLAF (FR) 1979-04-19 WO claimed
US-4145320-A BOUND TO POLY-ACRYLIC OR METHACRYLIC UNITS THROUGH OXYALKYLENIC, AMINOALKYLENIC, OR OXYAMINOALKYLENIC CHAINS FERRUTI PAOLO 1979-03-20 US claimed
US-4140850-A IMMUNOSUPPRESSIVE, VIRICIDES, SILYLATION, CYCLIZATION, DESILYLATION THE UPJOHN COMPANY (US) 1979-02-20 US claimed
US-4053475-A ANTI-ALLERGIC AGENTS STERLING DRUG INC. (US) 1977-10-11 US claimed
US-4028315-A Solid phase synthesis of peptides E. R. SQUIBB & SONS, INC. (US) 1977-06-07 US claimed
US-3983120-A HYPOTENSIVES, ANTICLOTTING BRISTOL-MYERS COMPANY (US) 1976-09-28 US claimed
US-RE28809-E Preparation of starch esters NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1976-05-11 US claimed