Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | MGLL | Q99685 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1325 | 0.91 | FAAH (0.45) | FAAHMGLLALDH1A1LMNAEGLN3 | |
| SCHEMBL15846673 | 0.91 | FAAH (0.45) | FAAHMGLLALDH1A1LMNAEGLN3 | |
| Hydrochloric Acid SCHEMBL6226784 | 0.88 | FAAH (0.44) | FAAHMGLLALDH1A1LMNAEGLN3 | |
| SCHEMBL2194853 | 0.88 | FAAH (0.44) | FAAHMGLLALDH1A1LMNAEGLN3 | |
| Phosphine SCHEMBL31680518 | 0.88 | FAAH (0.44) | FAAHMGLLALDH1A1LMNAEGLN3 | |
| SCHEMBL10814524 | 0.88 | FAAH (0.44) | FAAHMGLLALDH1A1LMNAEGLN3 | |
| Hydrogen Sulfide SCHEMBL10814521 | 0.88 | FAAH (0.44) | FAAHMGLLALDH1A1LMNAEGLN3 | |
| SCHEMBL12667290 | 0.86 | FAAH (0.41) | FAAHMGLLALDH1A1LMNAEGLN3 | |
| Methylene Chloride SCHEMBL4130957 | 0.82 | ALDH1A1 (0.42) | FAAHMGLLALDH1A1LMNAEGLN3 | |
| SCHEMBL2610160 | 0.82 | FAAH (0.41) | FAAHMGLLALDH1A1LMNAEGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211990-A1 | BICYCLIC HETEROCYCLIC AMIDE INHIBITORS OF NA V1.8 FOR THE TREATMENT OF PAIN | SITEONE THERAPEUTICS, INC. (US) | 2023-11-02 | — | — | WO | disclosed |
| US-20230339958-A1 | NON-HYDRATED KETONE INHIBITORS OF NAV1.7 FOR THE TREATMENT OF PAIN | SITEONE THERAPEUTICS, INC. | 2023-10-26 | — | — | US | disclosed |
| US-20230339958-A1 | NON-HYDRATED KETONE INHIBITORS OF NAV1.7 FOR THE TREATMENT OF PAIN | SITEONE THERAPEUTICS, INC. | 2023-10-26 | — | — | US | disclosed |
| WO-2022036297-A1 | NON-HYDRATED KETONE INHIBITORS OF NAV1.7 FOR THE TREATMENT OF PAIN | SITEONE THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |
| CN-109419247-A | The preservation container of vegetables | 欧卡股份有限公司 | 2019-03-05 | — | — | CN | disclosed |
| US-20170298051-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | THE UNIVERSITY OF TOKYO (JP) | 2017-10-19 | — | — | US | disclosed |
| US-20170298051-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | THE UNIVERSITY OF TOKYO (JP) | 2017-10-19 | — | — | US | disclosed |
| US-9493428-B2 | Process for the preparation of a chiral compound | SANDOZ AG (CH) | 2016-11-15 | — | — | US | disclosed |
| US-9315475-B2 | HIV protease inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-04-19 | — | — | US | disclosed |
| US-9040539-B2 | Process for the preparation of chiral triazolones | SANDOZ AG (CH) | 2015-05-26 | — | — | US | disclosed |
| US-20140343053-A1 | TRIAZOLOPYRIDINONE PDE10 INHIBITORS | MERCK SHARPE & DOHME CORP. (US) | 2014-11-20 | — | — | US | disclosed |
| US-20140303184-A1 | PROCESS FOR THE PREPARATION OF A CHIRAL COMPOUND | SANDOZ AG (CH) | 2014-10-09 | — | — | US | disclosed |
| US-20140200197-A1 | HIV PROTEASE INHIBITORS | MERCK SHARP & DOHME LLC | 2014-07-17 | — | — | US | disclosed |
| US-20130210833-A1 | PROCESS FOR THE PREPARATION OF CHIRAL TRIAZOLONES | SANDOZ AG (CH) | 2013-08-15 | — | — | US | disclosed |
| US-20130102079-A1 | POLYAMINE-CONTAINING POLYMERS AND METHODS OF SYNTHESIS AND USE | ALBERTA INNOVATES - TECHNOLOGY FUTURES (CA) | 2013-04-25 | — | — | US | disclosed |
| US-7928233-B2 | Spiroindolinone pyridine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2011-04-19 | — | — | US | disclosed |
| US-20100204257-A1 | SPIROINDOLINONE PYRIDINE DERIVATIVES | CHEN LI | 2010-08-12 | — | — | US | disclosed |
| US-20090312338-A1 | Novel Tricyclic Compounds | ABBOTT LABORATORIES (US) | 2009-12-17 | — | — | US | disclosed |
| US-20090312338-A1 | Novel Tricyclic Compounds | ABBOTT LABORATORIES (US) | 2009-12-17 | — | — | US | disclosed |
| US-20090233911-A2 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | NV REMYND (BE) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204257-A1 | SPIROINDOLINONE PYRIDINE DERIVATIVES | RB1, KRAS, WEE1 | FAAH 4880/4885MGLL 4863/4885ALDH1A1 701/4885 |
| US-20140303184-A1 | PROCESS FOR THE PREPARATION OF A CHIRAL COMPOUND | CYP3A4, CYP3A5, CYP4B1 | FAAH 3736/4885MGLL 3154/4885ALDH1A1 1533/4885 |
| US-20140343053-A1 | TRIAZOLOPYRIDINONE PDE10 INHIBITORS | PDE12, PDE10A, PDE5A | FAAH 1320/4885MGLL 2862/4885ALDH1A1 1058/4885 |
| US-20090233911-A2 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SNCA, HTT, PARK7 | FAAH 2797/4885MGLL 3668/4885ALDH1A1 1930/4885 |
| US-20090312338-A1 | Novel Tricyclic Compounds | CYP11B2, CYP11B1, ABCB1 | FAAH 2655/4885MGLL 4208/4885ALDH1A1 431/4885 |
| US-20230339958-A1 | NON-HYDRATED KETONE INHIBITORS OF NAV1.7 FOR THE TREATMENT OF PAIN | SCN7A, SCN10A, HCN3 | FAAH 393/4885MGLL 1687/4885ALDH1A1 2668/4885 |
| US-20140200197-A1 | HIV PROTEASE INHIBITORS | SERPINB1, PREP, PRSS1 | FAAH 1949/4885MGLL 880/4885ALDH1A1 2437/4885 |
| US-20130210833-A1 | PROCESS FOR THE PREPARATION OF CHIRAL TRIAZOLONES | CYP3A4, CYP3A43, CYP3A5 | FAAH 4746/4885MGLL 4275/4885ALDH1A1 2623/4885 |
| US-20170298051-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | ADIPOR1, ADIPOR2, CCKAR | FAAH 402/4885MGLL 1456/4885ALDH1A1 1802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.