Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 7/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13250812 | 0.96 | MAPT (0.43) | MAPTHSD11B1TLR8CASRBCL2L1 | |
| SCHEMBL14264198 | 0.96 | MAPT (0.43) | MAPTHSD11B1TLR8CASRBCL2L1 | |
| SCHEMBL15760413 | 0.90 | ESR1 (0.34) | MAPTAREZH2 | |
| SCHEMBL18179357 | 0.90 | SMN1; SMN2 (0.35) | MAPTHSD11B1TLR8MCL1AR | |
| SCHEMBL18179336 | 0.89 | SMN1; SMN2 (0.34) | MAPTHSD11B1TLR8MCL1AR | |
| SCHEMBL12433514 | 0.87 | MAPT (0.50) | MAPTHSD11B1TLR8CASRBCL2L1 | |
| SCHEMBL2628163 | 0.85 | TLR8 (0.49) | MAPTHSD11B1TLR8CASRBCL2L1 | |
| SCHEMBL13250811 | 0.85 | MAPT (0.45) | MAPTHSD11B1TLR8CASRBCL2L1 | |
| SCHEMBL18179329 | 0.84 | AR (0.33) | MAPTHSD11B1AR | |
| SCHEMBL12433519 | 0.84 | MAPT (0.41) | MAPTHSD11B1TLR8CASRBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431676-B2 | Aromatic compound and sulfonated polyarylene polymer | JSR CORPORATION (JP) | 2013-04-30 | — | — | US | disclosed |
| US-20100174042-A1 | AROMATIC COMPOUND AND SULFONATED POLYARYLENE POLYMER | JSR CORPORATION (JP) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174042-A1 | AROMATIC COMPOUND AND SULFONATED POLYARYLENE POLYMER | SCO2, CBR1, CNOT1 | MAPT 3426/4885HSD11B1 915/4885TLR8 686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.