SCHEMBL13250970

SCHEMBL13250970

Fc1ccc(-c2cc(-c3ccccc3-c3ccccc3)c3ccc4c(-c5ccc(F)cc5)cc(-c5ccccc5-c5ccccc5)c5ccc2c3c45)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.42
PTGS1 P23219 2/20 0.42
GRM2 Q14416 2/20 0.42
NR4A2 P43354 1/20 0.39
MKNK1 Q9BUB5 1/20 0.38
MKNK2 Q9HBH9 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
CYP2C19 P33261 1/20 0.38
PTK2B Q14289 1/20 0.38
METAP2 P50579 1/20 0.38
TOP1 P11387 2/20 0.38
GCGR P47871 1/20 0.38
MAPK14 Q16539 1/20 0.38
ALDH1A3 P47895 1/20 0.38
ADORA1 P30542 2/20 0.37
ADORA2A P29274 1/20 0.37
MAPT P10636 1/20 0.37
MAP2K4 P45985 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13251083 1.00 PTGS2 (0.42) PTGS2PTGS1GRM2NR4A2MKNK1
SCHEMBL15945804 0.93 GRM2 (0.46) PTGS2PTGS1GRM2NR4A2MKNK1
SCHEMBL13251076 0.93 GRM2 (0.46) PTGS2PTGS1GRM2NR4A2MKNK1
SCHEMBL13250966 0.93 GRM2 (0.46) PTGS2PTGS1GRM2NR4A2MKNK1
SCHEMBL13251081 0.91 GRM2 (0.45) PTGS1GRM2NR4A2MKNK1MKNK2
SCHEMBL13250969 0.91 GRM2 (0.45) PTGS1GRM2NR4A2MKNK1MKNK2
SCHEMBL13251147 0.88 GRM2 (0.44) GRM2NR4A2MKNK1MKNK2CYP1A2
SCHEMBL13250991 0.88 GRM2 (0.44) GRM2NR4A2MKNK1MKNK2CYP1A2
SCHEMBL13251107 0.88 GRM2 (0.44) GRM2NR4A2MKNK1MKNK2CYP1A2
SCHEMBL5651928 0.87 BACE1 (0.42) PTGS2HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940409-B2 Organic light emitting material and organic light emitting device using the same LG DISPLAY CO., LTD. (KR) 2015-01-27 US disclosed
US-8940409-B2 Organic light emitting material and organic light emitting device using the same LG DISPLAY CO., LTD. (KR) 2015-01-27 US disclosed
US-20100164374-A1 Organic light emitting material and organic light emitting device using the same LG DISPLAY CO., LTD. (KR) 2010-07-01 US disclosed
US-20100164374-A1 Organic light emitting material and organic light emitting device using the same LG DISPLAY CO., LTD. (KR) 2010-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100164374-A1 Organic light emitting material and organic light emitting device using the same CRY1, L3MBTL4, TMSB4X PTGS2 3889/4885PTGS1 3928/4885GRM2 1527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.