SCHEMBL1325112

SCHEMBL1325112

CC(=COCOCCO)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2123382 0.85 MEN1 (0.42) TSHRALDH1A1MAPK1MEN1KMT2A
SCHEMBL714155 0.85 MEN1 (0.42) TSHRALDH1A1MAPK1MEN1KMT2A
SCHEMBL715215 0.85 MEN1 (0.42) TSHRALDH1A1MAPK1MEN1KMT2A
SCHEMBL502736 0.85 MEN1 (0.42) TSHRALDH1A1MAPK1MEN1KMT2A
SCHEMBL170593 0.84 TSHR (0.32) TSHR
SCHEMBL10985217 0.84 TSHR (0.32) TSHR
Di(Hydroxyethyl)Ether SCHEMBL28477685 0.83 ALDH1A1 (0.41) TSHRALDH1A1MAPK1MEN1KMT2A
Ether SCHEMBL29157255 0.79 ALDH1A1 (0.41) TSHRALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL28476954 0.78 TSHR (0.40) TSHRALDH1A1MAPK1MEN1KMT2A
SCHEMBL28506569 0.77 PTGS1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9341946-B2 Photosensitive resin composition, pattern formed using same and display panel comprising same LG CHEM, LTD. (KR) 2016-05-17 US disclosed
US-9034561-B2 Photosensitive composition comprising an acrylate compound LG CHEM, LTD. (KR) 2015-05-19 US disclosed
US-8742005-B2 Acrylate-based compounds and photosensitive composition comprising the same LG CHEM, LTD. (KR) 2014-06-03 US disclosed
US-8552082-B2 Alkali-soluble polymer compound and photosensitive resin composition using the same LG CHEM, LTD. (KR) 2013-10-08 US disclosed
US-20130244182-A1 PHOTOSENSITIVE COMPOSITION COMPRISING AN ACRYLATE COMPOUND LG CHEM, LTD. (KR) 2013-09-19 US disclosed
US-20130034814-A1 SILANE-BASED COMPOUNDS AND PHOTOSENSITIVE RESIN COMPOSITION COMPRISING THE SAME LG CHEM, LTD. (KR) 2013-02-07 US disclosed
US-20120156619-A1 ACRYLATE-BASED COMPOUNDS AND PHOTOSENSITIVE COMPOSITION COMPRISING THE SAME LG CHEM, LTD. (KR) 2012-06-21 US disclosed
US-8168369-B2 Photoactive compound and photosensitive resin composition containing the same LG CHEM, LTD. (KR) 2012-05-01 US disclosed
US-20110318692-A1 PHOTOACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING THE SAME LG CHEM, LTD. (KR) 2011-12-29 US disclosed
US-20110269867-A1 ALKALI-SOLUBLE POLYMER COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME LG CHEM. LTD. (KR) 2011-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110318692-A1 PHOTOACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING THE SAME CCNT1, RFT1, SULT1A1 TSHR 4078/4885ALDH1A1 984/4885MAPK1 828/4885
US-20130034814-A1 SILANE-BASED COMPOUNDS AND PHOTOSENSITIVE RESIN COMPOSITION COMPRISING THE SAME CD47, EPCAM, EED TSHR 4844/4885ALDH1A1 985/4885MAPK1 3853/4885
US-20120156619-A1 ACRYLATE-BASED COMPOUNDS AND PHOTOSENSITIVE COMPOSITION COMPRISING THE SAME TYR, PAH, ACR TSHR 4719/4885ALDH1A1 79/4885MAPK1 2621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.