Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13255487 | 0.89 | MAPT (0.40) | KMT2AALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL13255494 | 0.87 | KDM4E (0.40) | KMT2AALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL13255490 | 0.84 | L3MBTL1 (0.44) | KMT2AALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL13255607 | 0.84 | MEN1 (0.42) | KMT2AALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL13850747 | 0.84 | GRM2 (0.43) | ALDH1A1KDM4EMAPTGAAL3MBTL1 | |
| SCHEMBL13851265 | 0.83 | GRM2 (0.39) | ALDH1A1KDM4EMAPTGAAGRM2 | |
| SCHEMBL13850821 | 0.83 | GRM2 (0.46) | GRM2PARP1LMNASMN1; SMN2 | |
| SCHEMBL13255419 | 0.82 | MEN1 (0.41) | KMT2AALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL13925840 | 0.82 | GRM2 (0.37) | GRM2PARP1MAOB | |
| SCHEMBL13255605 | 0.82 | MEN1 (0.38) | KMT2AALDH1A1KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759372-B2 | Nitrogen-containing heteroaryl compounds having inhibitory activity against HIV integrase | SHIONOGI & CO., LTD. (JP) | 2010-07-20 | — | — | US | disclosed |