SCHEMBL13255602

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13850822	0.93	GRM2 (0.42)	MAPTGRM2KDM5AKDM5BGAA
	SCHEMBL13850781	0.92	MAPT (0.42)	MAPTGRM2PLA2G2AFFAR4KDM5A
	SCHEMBL13255607	0.91	MEN1 (0.42)	MAPTGAAALDH1A1HPGDKDM4E
	SCHEMBL13850747	0.91	GRM2 (0.43)	MAPTGRM2GAAALDH1A1HPGD
	SCHEMBL13255611	0.90	GRM2 (0.39)	GRM2KDM5AKDM5BGAAKDM4E
	SCHEMBL13255620	0.89	LMNA (0.40)	GRM2KDM5AKDM5BALDH1A1SMN1; SMN2
	SCHEMBL13850749	0.89	MAPT (0.43)	MAPTGRM2PLA2G2AFFAR4KDM5A
	SCHEMBL13851246	0.89	MAPT (0.39)	MAPTPLA2G2AFFAR4KDM5AKDM5B
	SCHEMBL13850761	0.89	MAPT (0.43)	MAPTPLA2G2AFFAR4ALDH1A1HPGD
	SCHEMBL14193471	0.89	MAPT (0.42)	MAPTGRM2FFAR4KDM5AKDM5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.