Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 2/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21584443 | 0.89 | MEP1B (0.36) | DHPSMEP1BDPP4HTR1AHTR1D | |
| SCHEMBL13256004 | 0.85 | KDM4E (0.37) | DHPSMEP1BDPP4KDM4EALDH1A1 | |
| SCHEMBL1918698 | 0.81 | KDM4E (0.40) | DHPSMEP1BDPP4KDM4EALDH1A1 | |
| SCHEMBL12338396 | 0.81 | MEP1B (0.35) | DHPSMEP1BDPP4HTR1AHTR1D | |
| SCHEMBL11918062 | 0.81 | MEP1B (0.33) | DHPSMEP1BDPP4 | |
| SCHEMBL1918080 | 0.80 | KDM4E (0.37) | DHPSMEP1BKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11918082 | 0.79 | MEP1B (0.33) | MEP1B | |
| SCHEMBL2596720 | 0.79 | DHPS (0.38) | DHPSMEP1BDPP4HTR1AHTR1D | |
| SCHEMBL1397098 | 0.79 | DHPS (0.51) | DHPSDPP4HTR1AHTR1DHTR2C | |
| SCHEMBL10285748 | 0.77 | MEP1B (0.34) | MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010092339-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-19 | — | — | WO | disclosed |