Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.33 |
| ▸ | DHPS | P49366 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13256089 | 0.85 | DHPS (0.36) | KDM4EALDH1A1MEP1BHSD17B10DHPS | |
| SCHEMBL21584443 | 0.84 | MEP1B (0.36) | KDM4EALDH1A1MEP1BHSD17B10DHPS | |
| SCHEMBL719379 | 0.82 | TAS1R3 (0.38) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL12364193 | 0.79 | MEP1B (0.36) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL12338398 | 0.79 | ALDH1A1 (0.35) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL12338396 | 0.78 | MEP1B (0.35) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL718517 | 0.77 | MEP1B (0.37) | KDM4EALDH1A1PKMSMN1; SMN2MEP1B | |
| SCHEMBL12338387 | 0.77 | MEP1B (0.35) | KDM4EALDH1A1MEP1BHSD17B10TAS1R3 | |
| SCHEMBL12338395 | 0.76 | MEP1B (0.34) | KDM4EALDH1A1MEP1BHSD17B10DHPS | |
| SCHEMBL718435 | 0.76 | TAS1R3 (0.37) | KDM4EALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010092339-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-19 | — | — | WO | disclosed |