SCHEMBL13256152 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	CYP1A2	P05177	3/20	0.38

▸	KDM4E	B2RXH2	2/20	0.38

▸	AGTR1	P30556	1/20	0.38

▸	LMNA	P02545	1/20	0.38

▸	TSHR	P16473	1/20	0.36

▸	MAPK1	P28482	1/20	0.36

▸	MEN1	O00255	1/20	0.36

▸	CYP2C19	P33261	1/20	0.36

▸	KMT2A	Q03164	1/20	0.36

▸	AR	P10275	1/20	0.33

▸	FGFR1	P11362	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16785513	0.79	CYP1A2 (0.45)	CYP1A2KDM4EAGTR1LMNATSHR
SCHEMBL16785598	0.79	CYP1A2 (0.45)	CYP1A2KDM4EAGTR1LMNATSHR
SCHEMBL14896792	0.79	CYP1A2 (0.45)	CYP1A2KDM4EAGTR1LMNATSHR
SCHEMBL19365303	0.76	CYP1A2 (0.39)	CYP1A2KDM4EAGTR1LMNATSHR
SCHEMBL15999364	0.76	CYP1A2 (0.39)	CYP1A2KDM4EAGTR1LMNATSHR
SCHEMBL19670113	0.76	CYP1A2 (0.39)	CYP1A2KDM4EAGTR1LMNATSHR
SCHEMBL17618307	0.76	CYP1A2 (0.39)	CYP1A2KDM4EAGTR1LMNATSHR
SCHEMBL20098864	0.76	CYP1A2 (0.39)	CYP1A2KDM4EAGTR1LMNATSHR
SCHEMBL20163374	0.73	THRB (0.35)	KMT2A
SCHEMBL6508045	0.73	HTR1A (0.42)	CYP1A2KDM4EAGTR1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010088574-A1	AZABENZIMIDAZOLES AND RELATED ANALOGS AS SIRTUIN MODULATORS	SIRTRIS PHARMACEUTICALS, INC. (US)	2010-08-05	—	—	WO	disclosed
WO-2010077947-A1	PHTHALAZINONE AND RELATED ANALOGS AS SIRTUIN MODULATORS	SIRTRIS PHARMACEUTICALS, INC. (US)	2010-07-08	—	—	WO	disclosed