Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491444 | 1.00 | HTR1A (0.42) | HTR1AHTR7KDM4ECYP1A2AGTR1 | |
| SCHEMBL11665347 | 0.84 | HTR1A (0.41) | HTR1AHTR7KDM4EKMT2ATSHR | |
| SCHEMBL11142307 | 0.77 | ADRB2 (0.51) | — | |
| SCHEMBL2110330 | 0.75 | KDM4E (0.38) | HTR1AHTR7KDM4ELMNAKMT2A | |
| SCHEMBL14300695 | 0.75 | KDM4E (0.36) | HTR1AHTR7KDM4EKMT2AMEN1 | |
| SCHEMBL6491397 | 0.74 | CYP1A2 (0.50) | KDM4ECYP1A2AGTR1LMNAKMT2A | |
| SCHEMBL6491400 | 0.74 | CYP1A2 (0.50) | KDM4ECYP1A2AGTR1LMNAKMT2A | |
| SCHEMBL14897614 | 0.74 | CYP1A2 (0.42) | KDM4ECYP1A2AGTR1LMNAKMT2A | |
| SCHEMBL14896681 | 0.74 | CYP1A2 (0.42) | KDM4ECYP1A2AGTR1LMNAKMT2A | |
| SCHEMBL13187505 | 0.74 | CYP1A2 (0.42) | KDM4ECYP1A2AGTR1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003140-A1 | 4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-01-13 | — | — | WO | disclosed |