Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.40 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13256322 | 0.85 | IDO1 (0.61) | CYP1A2HPGDCYP2D6CYP2C9ALOX15 | |
| SCHEMBL13256341 | 0.80 | IDO1 (0.69) | CYP1A2HPGDCYP2D6CYP2C9ALOX15 | |
| Hydrochloric Acid SCHEMBL3393491 | 0.79 | CYP1A2 (0.46) | CYP1A2HPGDCYP2D6CYP2C9ALOX15 | |
| SCHEMBL13256346 | 0.77 | IDO1 (0.53) | CYP1A2HPGDCYP2D6CYP2C9ALOX15 | |
| SCHEMBL13283510 | 0.77 | IDO1 (0.47) | CYP1A2HPGDCYP2D6CYP2C9ALOX15 | |
| SCHEMBL5149992 | 0.72 | MAPK1 (0.52) | CYP1A2HPGDPDE7APDE7BMAPT | |
| SCHEMBL28263084 | 0.71 | NPC1 (0.51) | CYP1A2HPGDPDE7APDE7BKCNMA1 | |
| SCHEMBL3776333 | 0.70 | IDO1 (0.63) | CYP1A2HPGDCYP2D6CYP2C9ALOX15 | |
| SCHEMBL67536 | 0.70 | MAPK1 (0.53) | CYP1A2HPGDPDE7APDE7BMAPT | |
| SCHEMBL535352 | 0.70 | MAPK1 (0.53) | CYP1A2HPGDPDE7APDE7BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184851-A1 | INHIBITION OF CELL PROLIFERATION | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-07-22 | — | — | US | disclosed |
| US-20100184851-A1 | INHIBITION OF CELL PROLIFERATION | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-07-22 | — | — | US | disclosed |
| WO-2010025448-A2 | INHIBITION OF CELL PROLIFERATION | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184851-A1 | INHIBITION OF CELL PROLIFERATION | MKI67, RB1, RAF1 | CYP1A2 3630/4885HPGD 2694/4885CYP2D6 3598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.