Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.57 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13257659 | 1.00 | HPGD (0.69) | HPGDKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL13257616 | 0.88 | ALDH1A1 (0.54) | HPGDKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL13483218 | 0.82 | CNR1 (0.57) | HPGDKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL24567732 | 0.82 | ACACB (0.60) | HPGDKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL13753578 | 0.82 | GPR139 (0.56) | HPGDKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL13257657 | 0.81 | HPGD (0.71) | HPGDKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL13257653 | 0.81 | HPGD (0.71) | HPGDKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL13257710 | 0.81 | HPGD (0.71) | HPGDKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL13257828 | 0.81 | ALDH1A1 (0.53) | HPGDKMT2ASMN1; SMN2HTTKDM4E | |
| SCHEMBL13257604 | 0.81 | HPGD (0.74) | HPGDKMT2AMEN1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010088450-A2 | METHODS FOR TREATING DISEASES ASSOCIATED WITH THE MODULATION OF SERCA | CELLADON CORPORATION (US) | 2010-08-05 | — | — | WO | disclosed |