Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13257668 | 0.83 | ALDH1A1 (0.57) | ALDH1A1USP2TSHRMAPK1NPC1 | |
| SCHEMBL13257646 | 0.81 | HPGD (0.69) | ALDH1A1GPR139POLBKMT2AHPGD | |
| SCHEMBL13257659 | 0.81 | HPGD (0.69) | ALDH1A1GPR139POLBKMT2AHPGD | |
| SCHEMBL13257696 | 0.80 | POLB (0.63) | ALDH1A1USP2TSHRMAPK1NPC1 | |
| SCHEMBL13257859 | 0.78 | ALDH1A1 (0.56) | ALDH1A1USP2TSHRMAPK1NPC1 | |
| SCHEMBL24567732 | 0.78 | ACACB (0.60) | ALDH1A1MAPK1RAB9AGPR139KMT2A | |
| SCHEMBL13753578 | 0.78 | GPR139 (0.56) | ALDH1A1GPR139KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL22151161 | 0.77 | GPR139 (0.55) | ALDH1A1GPR139KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL13257616 | 0.77 | ALDH1A1 (0.54) | ALDH1A1GPR139KMT2AHPGDMAPT | |
| SCHEMBL13257645 | 0.76 | ALDH1A1 (0.50) | ALDH1A1USP2TSHRMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010088450-A2 | METHODS FOR TREATING DISEASES ASSOCIATED WITH THE MODULATION OF SERCA | CELLADON CORPORATION (US) | 2010-08-05 | — | — | WO | disclosed |