Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118963 | 0.78 | TRPA1 (0.30) | TRPA1TSHR | |
| SCHEMBL267284 | 0.74 | CTSC (0.31) | — | |
| SCHEMBL11195966 | 0.74 | — | — | |
| SCHEMBL28218321 | 0.71 | CYP1A2 (0.35) | — | |
| SCHEMBL11684530 | 0.71 | — | — | |
| SCHEMBL4433093 | 0.69 | — | — | |
| SCHEMBL595666 | 0.69 | — | — | |
| SCHEMBL457395 | 0.69 | — | — | |
| SCHEMBL96104 | 0.69 | — | — | |
| SCHEMBL7453028 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8349222-B2 | Twisted π-electron system chromophore compounds with very large molecular hyperpolarizabilities and related compositions and devices | NORTHWESTERN UNIVERSITY (US) | 2013-01-08 | — | — | US | disclosed |
| US-20110278512-A1 | Twisted Pi-Electron System Chromophore Compounds with Very Large Molecular Hyperpolarizabilities and Related Compositions and Devices | Northwestem University (US) | 2011-11-17 | — | — | US | disclosed |
| US-7968016-B2 | Twisted π-electron system chromophore compounds with very large molecular hyperpolarizabilities and related compositions and devices | NORTHWESTERN UNIVERSITY (US) | 2011-06-28 | — | — | US | disclosed |
| US-7824582-B2 | Twisted π-electron system chromophore compounds with very large molecular hyperpolarizabilities and related compositions and devices | NORTHWESTERN UNIVERSITY (US) | 2010-11-02 | — | — | US | disclosed |
| US-20100273919-A1 | TWISTED PI-ELECTRON SYSTEM CHROMOPHORE COMPOUNDS WITH VERY LARGE MOLECULAR HYPERPOLARIZABILITIES AND RELATED COMPOSITIONS AND DEVICES | NATIONAL SCIENCE FOUNDATION | 2010-10-28 | — | — | US | disclosed |
| US-20060237368-A1 | Twisted pi-electron system chromophore compounds with very large molecular hyperpolarizabilities and related compositions and devices | NATIONAL SCIENCE FOUNDATION | 2006-10-26 | — | — | US | disclosed |
| WO-2006102620-A2 | TWISTED π-ELECTRON SYSTEM CHROMOPHORE COMPOUNDS WITH VERY LARGE MOLECULAR HYPERPOLARIZABILITIES AND RELATED COMPOSITIONS AND DEVICES | NORTHWESTERN UNIVERSITY (US) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273919-A1 | TWISTED PI-ELECTRON SYSTEM CHROMOPHORE COMPOUNDS WITH VERY LARGE MOLECULAR HYPERPOLARIZABILITIES AND RELATED COMPOSITIONS AND DEVICES | PAX3, OPA1, LAGE3 | TRPA1 1515/4885TSHR 3813/4885 |
| US-20110278512-A1 | Twisted Pi-Electron System Chromophore Compounds with Very Large Molecular Hyperpolarizabilities and Related Compositions and Devices | PAX3, OPA1, LAGE3 | TRPA1 1515/4885TSHR 3813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.