Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SQLE | Q14534 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731847 | 0.81 | ALDH1A1 (0.48) | PYCR1CYP3A4TSHRBLMALDH1A1 | |
| SCHEMBL46288 | 0.78 | KCNH2 (0.58) | PYCR1CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL28486049 | 0.76 | KCNH2 (0.61) | PYCR1CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL17188617 | 0.76 | CYP3A4 (0.42) | PYCR1CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL26668490 | 0.76 | PYCR1 (0.41) | PYCR1CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL29430122 | 0.74 | PYCR1 (0.46) | PYCR1CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL3397750 | 0.73 | CYP1A2 (0.58) | CYP3A4CYP2C9CYP2C19CYP1A2THPO | |
| SCHEMBL13259165 | 0.73 | TSHR (0.42) | PYCR1CYP3A4CYP2C19TSHRBLM | |
| SCHEMBL19420119 | 0.73 | PYCR1 (0.47) | PYCR1CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL13259183 | 0.72 | MAOB (0.64) | PYCR1CYP3A4CYP1A2TSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168441-A1 | PROCESS FOR PRODUCTION OF SUBSTITUTED BENZENE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168441-A1 | PROCESS FOR PRODUCTION OF SUBSTITUTED BENZENE | MYB, KCNH2, INTS9 | PYCR1 1638/4885CYP3A4 204/4885CYP2C9 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.