Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Testolactone SCHEMBL2300061 | 0.84 | CYP19A1 (1.00) | CYP19A1LMNAMAPTCYP3A4 | |
| Testolactone SCHEMBL4053 | 0.84 | CYP19A1 (1.00) | CYP19A1LMNAMAPTCYP3A4 | |
| SCHEMBL25992396 | 0.82 | CYP19A1 (0.79) | CYP19A1LMNAMAPTCYP3A4 | |
| SCHEMBL12857031 | 0.81 | LMNA (0.69) | CYP19A1LMNAMAPTCYP3A4 | |
| SCHEMBL1144570 | 0.81 | LMNA (0.69) | CYP19A1LMNAMAPTCYP3A4 | |
| Testolactone SCHEMBL5083091 | 0.79 | CYP19A1 (0.89) | CYP19A1LMNAMAPTCYP3A4 | |
| SCHEMBL13259634 | 0.79 | CYP19A1 (0.62) | CYP19A1LMNAMAPTCYP3A4 | |
| SCHEMBL8980226 | 0.79 | GUSB (0.62) | CYP19A1LMNAMAPTCYP3A4 | |
| Androstenedone SCHEMBL3758714 | 0.78 | CYP19A1 (1.00) | CYP19A1LMNAMAPTCYP3A4 | |
| Androstenedone SCHEMBL172864 | 0.78 | CYP19A1 (1.00) | CYP19A1LMNAMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519051-A | AROMATASE INHIBITORS USEFUL FOR TREATMENT OF DISEASES CAUSED BY EXCESS OF ESTROGEN, FOR EXAMPLE, BREAST CANCER, UTERINE CANCER | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| EP-0582713-A1 | NOVEL OXA- OR AZASTEROID DERIVATIVE | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1994-02-16 | — | — | EP | disclosed |