Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13262159 | 0.89 | ALOX5AP (0.49) | ALOX5APLMNA | |
| SCHEMBL10199229 | 0.86 | KDM4E (0.48) | ALOX5AP | |
| SCHEMBL10197152 | 0.83 | ALOX5AP (0.46) | ALOX5APCYP2C9 | |
| SCHEMBL10198931 | 0.82 | ALOX5AP (0.43) | ALOX5APLMNAPTGS2 | |
| SCHEMBL14397218 | 0.81 | ALOX5AP (0.55) | ALOX5APNR1I2CYP2C9PTGS2 | |
| SCHEMBL2991950 | 0.80 | ALOX5AP (0.42) | ALOX5AP | |
| SCHEMBL2995893 | 0.80 | ALOX5AP (0.38) | ALOX5APLMNA | |
| SCHEMBL13262244 | 0.79 | ALOX5AP (0.47) | ALOX5AP | |
| SCHEMBL707986 | 0.77 | ALOX5AP (0.53) | ALOX5APPTGS2 | |
| SCHEMBL14397114 | 0.77 | ALOX5AP (0.53) | ALOX5APPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168076-A1 | DIPHENYL SUBSTITUTED ALKANES | MERCK SHARP & DOHME CORP. | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168076-A1 | DIPHENYL SUBSTITUTED ALKANES | ALOX5, ALOX15, ALOX15B | ALOX5AP 14/4885LMNA 1616/4885NR1I2 332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.