Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3175264 | 0.86 | MAPT (0.49) | AGTR1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL29915668 | 0.84 | ALDH1A1 (0.57) | AGTR1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL587283 | 0.84 | ALDH1A1 (0.57) | AGTR1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL2510669 | 0.84 | MAPT (0.48) | AGTR1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6293999 | 0.83 | KDM4E (0.51) | AGTR1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28409108 | 0.83 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDMAPTTP53 | |
| SCHEMBL10712712 | 0.82 | GAA (0.46) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11076023 | 0.81 | HPGD (0.47) | AGTR1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5707634 | 0.81 | POLB (0.51) | AGTR1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL5180569 | 0.80 | GAA (0.48) | AGTR1KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9526924-B2 | Composition comprising a screening agent of the lipophilic 2-hydroxybenzophenone type and a silicon-compromising s-triazine substituted by at least two alkylaminobenzoate groups | L'OREAL (FR) | 2016-12-27 | — | — | US | disclosed |
| EP-2470158-B1 | COMPOSITION CONTAINING AT LEAST ONE LIPOPHILIC 2-HYDROXYBENZOPHENONE FILTER AND A SILICON S-TRIAZINE SUBSTITUTED BY AT LEAST TWO ALKYLAMINOBENZOATE GROUPS | ORÉAL L (FR) | 2016-10-05 | — | — | EP | disclosed |
| CN-101535412-B | New ds DNA binding fluorescent dyes | HOFFMANN LA ROCHE | 2014-05-07 | — | — | CN | disclosed |
| US-20120201767-A1 | COMPOSITION COMPRISING A SCREENING AGENT OF THE LIPOPHILIC 2-HYDROXYBENZOPHENONE TYPE AND A SILICON-COMPRISING S-TRIAZINE SUBSTITUTED BY AT LEAST TWO ALKYLAMINOBENZOATE GROUPS | L'OREAL (FR) | 2012-08-09 | — | — | US | disclosed |
| EP-2470158-A2 | COMPOSITION CONTAINING AT LEAST ONE LIPOPHILIC 2-HYDROXYBENZOPHENONE FILTER AND A SILICON S-TRIAZINE SUBSTITUTED BY AT LEAST TWO ALKYLAMINOBENZOATE GROUPS | L'Oréal (FR) | 2012-07-04 | — | — | EP | disclosed |
| US-8058431-B2 | Fluorescent double stranded DNA binding dyes | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-11-15 | — | — | US | disclosed |
| WO-2011023886-A2 | COMPOSITION CONTAINING AT LEAST ONE LIPOPHILIC 2-HYDROXYBENZOPHENONE FILTER AND A SILICON S-TRIAZINE SUBSTITUTED BY AT LEAST TWO ALKYLAMINOBENZOATE GROUPS | L'OREAL (FR) | 2011-03-03 | — | — | WO | disclosed |
| EP-2087043-B1 | NEW DS DNA BINDING FLUORESCENT DYES | ROCHE DIAGNOSTICS GMBH (DE) | 2010-08-04 | — | — | EP | disclosed |
| US-20090275037-A1 | FLUORESCENT DOUBLE STRANDED DNA BINDING DYES | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2009-11-05 | — | — | US | disclosed |
| CN-101535412-A | New ds DNA binding fluorescent dyes | ROCHE DIAGNOSTICS GMBH (CH) | 2009-09-16 | — | — | CN | disclosed |
| EP-2087043-A1 | NEW DS DNA BINDING FLUORESCENT DYES | Roche Diagnostics GmbH (DE) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008052742-A1 | NEW DS DNA BINDING FLUORESCENT DYES | ROCHE DIAGNOSTICS GMBH (DE) | 2008-05-08 | — | — | WO | disclosed |
| US-6884801-B1 | Imidazoline derivatives as alpha-1A adrenoceptor ligands | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-26 | — | — | US | disclosed |
| US-6872727-B1 | Polycyclic pyrimidine -2,4(1H,3H)-diones with functionalized alkyl residues at the 1- and/or 3-position(s); methods for their synthesis and pharmaceutical preparation | PRIVATES INSTITUT FUR BIOMEDIZINISCHE FORSCHUNG UND BERATUNG (DE) | 2005-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120201767-A1 | COMPOSITION COMPRISING A SCREENING AGENT OF THE LIPOPHILIC 2-HYDROXYBENZOPHENONE TYPE AND A SILICON-COMPRISING S-TRIAZINE SUBSTITUTED BY AT LEAST TWO ALKYLAMINOBENZOATE GROUPS | STS, TST, ARSA | AGTR1 3469/4885MEN1 3040/4885KMT2A 1431/4885 |
| US-20090275037-A1 | FLUORESCENT DOUBLE STRANDED DNA BINDING DYES | PCNA, DDB1, SSBP1 | AGTR1 2487/4885MEN1 1811/4885KMT2A 1395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.