SCHEMBL3175264

SCHEMBL3175264

C=CCNc1ccccc1C(=O)c1ccccc1NCC=C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.49
HPGD P15428 3/20 0.47
CYP1A2 P05177 1/20 0.47
ALDH1A1 P00352 7/20 0.47
TP53 P04637 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
LMNA P02545 2/20 0.44
HSD17B10 Q99714 1/20 0.42
CYP3A4 P08684 1/20 0.42
KDM4E B2RXH2 3/20 0.41
AGTR1 P30556 1/20 0.41
RAB9A P51151 1/20 0.41
CA1 P00915 1/20 0.41
CA9 Q16790 1/20 0.41
CCNA2 P20248 1/20 0.40
CCNE1 P24864 1/20 0.40
CDK2 P24941 1/20 0.40
HCAR3 P49019 1/20 0.40
GLA P06280 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL277817 0.90 MAPT (0.55) MAPTHPGDCYP1A2ALDH1A1TP53
SCHEMBL29915668 0.87 ALDH1A1 (0.57) MAPTHPGDCYP1A2ALDH1A1TP53
SCHEMBL2510669 0.87 MAPT (0.48) MAPTHPGDCYP1A2ALDH1A1TP53
SCHEMBL587283 0.87 ALDH1A1 (0.57) MAPTHPGDCYP1A2ALDH1A1TP53
SCHEMBL28409108 0.86 ALDH1A1 (0.48) MAPTHPGDCYP1A2ALDH1A1TP53
SCHEMBL1326322 0.86 AGTR1 (0.50) MAPTHPGDCYP1A2ALDH1A1TP53
SCHEMBL5707634 0.84 POLB (0.51) MAPTHPGDCYP1A2ALDH1A1TP53
Hydrochloric Acid SCHEMBL11076023 0.84 HPGD (0.47) MAPTHPGDCYP1A2ALDH1A1TP53
SCHEMBL5180569 0.83 GAA (0.48) MAPTHPGDCYP1A2ALDH1A1TP53
SCHEMBL11062628 0.83 KDM4E (0.62) MAPTHPGDCYP1A2ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7776507-B2 Photosensitive paste and manufacturing method of member for display panel TORAY INDUSTRIES, INC. (JP) 2010-08-17 US claimed
US-20090035452-A1 Photosensitive paste and manufacturing method of member for display panel TORAY INDUSTRIES, INC. (JP) 2009-02-05 US claimed
JP-8082922-A None JP disclosed
US-20240190106-A1 Manufacturing Methods of Decorative Surfaces AGFA NV (BE) 2024-06-13 US disclosed
US-12006440-B2 Radiation curable inkjet inks for interior decoration AGFA NV (BE) 2024-06-11 US disclosed
US-20240117207-A1 UV Curable Inkjet Inks and Inkjet Printing Methods AGFA NV (BE) 2024-04-11 US disclosed
EP-4347728-A1 UV LED FREE RADICAL CURABLE INKJET INKS AGFA NV (BE) 2024-04-10 EP disclosed
WO-2024061509-A1 PIGMENTED FREE RADICAL CURABLE INKJET INKS AGFA NV (BE) 2024-03-28 WO disclosed
EP-4339248-A1 PIGMENTED FREE RADICAL CURABLE INKJET INKS AGFA NV (BE) 2024-03-20 EP disclosed
US-11845874-B2 Radiation curable inkjet inks for interior decoration AGFA NV (BE) 2023-12-19 US disclosed
EP-4263731-A1 UV CURABLE INKJET INKS AND INKJET PRINTING METHODS AGFA NV (BE) 2023-10-25 EP disclosed
US-20090035452-A1 Photosensitive paste and manufacturing method of member for display panel TORAY INDUSTRIES, INC. (JP) 2009-02-05 US disclosed
EP-0939102-B1 Rubber compounds containing aromatic ketone polysulfides GOODYEAR TIRE & RUBBER (US) 2004-04-07 EP disclosed
US-6303821-B1 IMPROVE THE POLYMER-FILLER INTERACTION OF ELASTOMERS OR RUBBERS. THE GOODYEAR TIRE & RUBBER COMPANY 2001-10-16 US disclosed
US-6277926-B1 PROCESSING RUBBER BY MIXING WITH A BIS-(4-AMINOPHENYL)-CARBONYL-(1,4-PHENYLENE)-POLYSUFIDE TO INCREASE THE MOONEY VISCOSITY I.E. STIFFNESS; IMPROVED POLYMER/FILLER INTERACTION; RECEPTIVITY THE GOODYEAR TIRE & RUBBER COMPANY 2001-08-21 US disclosed
US-6075096-A BIS(ALKYLAMINO)BENZOPHENONES BRIDGED TOGETHER BY A POLYSULFIDE GROUP (SX, X=2-8) WHICH ACTS TO IMPROVE THE POLYMER-FILLER INTERACTION OF ELASTOMERS OR RUBBERS; FORMED COMPOSITE PRODUCTS SUCH AS TIRES, SHOE HEELS THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-06-13 US disclosed
EP-0939102-A2 Rubber compounds containing aromatic ketone polysulfides THE GOODYEAR TIRE & RUBBER COMPANY (US) 1999-09-01 EP disclosed
JP-H0882922-A ORIGINAL PLATE OF WATERLESS PLANOGRAPHIC PRINTING PLATE TORAY IND INC 1996-03-26 JP disclosed
US-4096144-A Process for preparing quinazolinone derivatives and their 2-(N-mono-substituted amino)-phenyl ketone intermediate derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-06-20 US disclosed
US-4071557-A Preparation of 2-substituted aminophenyl ketones SANDOZ, INC. (US) 1978-01-31 US disclosed