Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580876 | 0.82 | STK17B (0.49) | PDK1PDK2PDK3PDK4TDP1 | |
| SCHEMBL1337452 | 0.80 | TRPV4 (0.47) | PDK1PDK2PDK3PDK4ABCB1 | |
| SCHEMBL1725102 | 0.79 | IRAK4 (0.42) | ALDH1A1GAAMAPT | |
| SCHEMBL1727212 | 0.77 | TLR8 (0.39) | ABCB1TNFCCNCCDK8 | |
| SCHEMBL16109970 | 0.76 | PDK1 (0.42) | PDK1PDK2PDK3PDK4ABCB1 | |
| SCHEMBL1479396 | 0.75 | ABCB1 (0.37) | PDK1PDK2PDK3PDK4ABCB1 | |
| SCHEMBL13344272 | 0.75 | TDP1 (0.34) | PDK1PDK2PDK3PDK4TDP1 | |
| SCHEMBL4342787 | 0.74 | PDK1 (0.45) | PDK1PDK2PDK3PDK4ABCB1 | |
| SCHEMBL1724772 | 0.74 | DPP4 (0.46) | ABCB1MEN1KMT2A | |
| SCHEMBL12129767 | 0.74 | HSD11B1 (0.42) | PDK1PDK2PDK3PDK4ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210890-A1 | Oxadiazole derivatives as S1P1 receptor agonists | Almirall, S.A. (ES) | 2010-07-28 | — | — | EP | disclosed |