Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.32 |
| ▸ | TUBB | P07437 | 2/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16052950 | 0.78 | MAPT (0.42) | MAPTNPSR1EP300ALDH1A1CYP3A4 | |
| SCHEMBL31261040 | 0.78 | MAPT (0.42) | MAPTNPSR1EP300ALDH1A1CYP3A4 | |
| SCHEMBL13186794 | 0.78 | MAPT (0.42) | MAPTNPSR1EP300ALDH1A1CYP3A4 | |
| SCHEMBL30413681 | 0.77 | MAPT (0.41) | MAPTNPSR1EP300ALDH1A1CYP3A4 | |
| SCHEMBL21440016 | 0.77 | MAPT (0.41) | MAPTNPSR1EP300ALDH1A1CYP3A4 | |
| SCHEMBL27408256 | 0.75 | EP300 (0.47) | MAPTNPSR1EP300ALDH1A1CYP3A4 | |
| SCHEMBL30542553 | 0.75 | MAPT (0.53) | MAPTNPSR1EP300ALDH1A1CYP3A4 | |
| SCHEMBL6744216 | 0.75 | MAPT (0.53) | MAPTNPSR1EP300ALDH1A1CYP3A4 | |
| SCHEMBL5359171 | 0.74 | RAB9A (0.33) | MAPTALDH1A1CYP3A4POLBGAA | |
| SCHEMBL18472614 | 0.72 | ACHE (0.59) | MAPTALDH1A1CYP3A4KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074089-A1 | INDANYL COMPOUNDS | 第一三共株式会社 (JP) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010074088-A1 | CYCLIC AMINE COMPOUNDS | 第一三共株式会社 (JP) | 2010-07-01 | — | — | WO | disclosed |