SCHEMBL5359171

SCHEMBL5359171

Bc1c(F)cc(F)cc1OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.33
LMNA P02545 2/20 0.33
NFE2L2 Q16236 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
TUBB1 Q9H4B7 2/20 0.32
TRPA1 O75762 2/20 0.32
CYP3A4 P08684 2/20 0.32
NPC1 O15118 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
MAOB P27338 1/20 0.32
MAP2K1 Q02750 1/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
GAA P10253 1/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24840306 0.80 ACHE (0.48) RAB9ALMNANFE2L2MAPK1HTT
SCHEMBL13186794 0.77 MAPT (0.42) RAB9ALMNANFE2L2MAPK1HTT
SCHEMBL31261040 0.77 MAPT (0.42) RAB9ALMNANFE2L2MAPK1HTT
SCHEMBL10086105 0.76 TUBB1 (0.42) RAB9ALMNANFE2L2MAPK1HTT
SCHEMBL13086666 0.74 TUBB1 (0.39) RAB9ALMNANFE2L2MAPK1HTT
SCHEMBL5346004 0.74 CES2 (0.36) ALDH1A1
SCHEMBL13264129 0.74 MAPT (0.39) NFE2L2TUBB1CYP3A4NPC1ALDH1A1
SCHEMBL5019923 0.73 MAPT (0.38) RAB9ALMNANFE2L2MAPK1HTT
SCHEMBL1813756 0.73 SCN9A (0.38) RAB9ALMNANFE2L2MAPK1HTT
SCHEMBL1042344 0.73 ALOX5 (0.51) LMNANFE2L2HTTALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7217676-B2 Hydrophobization and silica for supported catalyst EXXON MOBIL CHEMICAL PATENTS INC. (US) 2007-05-15 US disclosed
EP-1704171-A2 HYDROPHOBIZATION AND SILICA FOR SUPPORTED CATALYST ExxonMobil Chemical Patents Inc. (US) 2006-09-27 EP disclosed
WO-2005075526-A2 HYDROPHOBIZATION AND SILICA FOR SUPPORTED CATALYST EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-08-18 WO disclosed
US-20050159299-A1 Hydrophobization and silica for supported catalyst EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-21 US disclosed