Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14992467 | 0.76 | — | — | |
| SCHEMBL14992608 | 0.76 | IMPDH2 (0.32) | — | |
| SCHEMBL13377252 | 0.75 | MEN1 (0.31) | — | |
| SCHEMBL14405201 | 0.74 | — | — | |
| SCHEMBL13263826 | 0.74 | CYP3A4 (0.35) | — | |
| SCHEMBL15393695 | 0.73 | RAPGEF4 (0.30) | — | |
| SCHEMBL15247375 | 0.71 | PTGS2 (0.36) | — | |
| SCHEMBL10174854 | 0.70 | HSP90AB1 (0.41) | — | |
| SCHEMBL14366115 | 0.70 | RAPGEF4 (0.36) | — | |
| SCHEMBL26676087 | 0.70 | PTGS2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754728-B2 | Adenine compound and use thereof | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-07-13 | — | — | US | disclosed |