Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21482768 | 0.86 | HTR7 (0.47) | KMT2AHSD17B10ALDH1A1HPGDALOX15 | |
| SCHEMBL27643700 | 0.85 | CES2 (0.44) | KMT2AMEN1HSD17B10ALDH1A1ALOX15 | |
| SCHEMBL22097354 | 0.84 | KMT2A (0.70) | KMT2AMEN1LMNAMAPK1CES2 | |
| SCHEMBL23594645 | 0.83 | CES2 (0.43) | KMT2AMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL25742812 | 0.82 | HSD17B10 (0.59) | KMT2AMEN1HSD17B10ALDH1A1HPGD | |
| SCHEMBL5568822 | 0.81 | MEN1 (0.71) | KMT2AMEN1HSD17B10ALDH1A1HPGD | |
| SCHEMBL13263814 | 0.81 | HPGD (0.44) | HSD17B10ALDH1A1HPGDALOX15TSHR | |
| SCHEMBL6744202 | 0.81 | F2R (0.56) | KMT2AMEN1HSD17B10ALDH1A1HPGD | |
| SCHEMBL6944180 | 0.80 | CES2 (0.57) | HSD17B10ALDH1A1HPGDALOX15TSHR | |
| SCHEMBL3924529 | 0.80 | PTPN1 (0.50) | KMT2AMEN1ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074088-A1 | CYCLIC AMINE COMPOUNDS | 第一三共株式会社 (JP) | 2010-07-01 | — | — | WO | disclosed |