Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.57 |
| ▸ | CES1 | P23141 | 3/20 | 0.57 |
| ▸ | ACKR3 | P25106 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29746067 | 0.85 | CES2 (0.61) | CES2CES1ACKR3 | |
| SCHEMBL196379 | 0.85 | CES2 (0.61) | CES2CES1ACKR3 | |
| SCHEMBL29688370 | 0.84 | MEN1 (0.49) | ACKR3ALDH1A1HPGDALOX15TSHR | |
| SCHEMBL176969 | 0.84 | HTT (0.54) | ALDH1A1HPGDALOX15TSHRRECQL | |
| SCHEMBL21482768 | 0.84 | HTR7 (0.47) | CES2CES1ACKR3ALDH1A1HPGD | |
| SCHEMBL20134974 | 0.84 | MEN1 (0.49) | ACKR3ALDH1A1HPGDALOX15TSHR | |
| SCHEMBL21780538 | 0.82 | F2R (0.56) | CES2CES1ACKR3ALDH1A1HPGD | |
| SCHEMBL11900526 | 0.82 | DGAT1 (0.56) | ACKR3ALDH1A1HPGDALOX15TSHR | |
| SCHEMBL8967743 | 0.82 | HPGD (0.46) | CES2CES1ALDH1A1HPGDALOX15 | |
| SCHEMBL11847285 | 0.81 | CES2 (0.57) | CES2CES1ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018109271-A1 | NEW BROMODOMAIN INHIBITORS | ORION CORPORATION (FI) | 2018-06-21 | — | — | WO | disclosed |
| EP-0927719-B1 | Triazole derivative or salt thereof, preparation process thereof as well as pharmaceutical containing said compound | SSP CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6204415-B1 | 2,2-DIFLUORO-2-ETHYLTHIOACETOPHENONE DERIVATIVES OF GIVEN FORMULA WHICH HAVE USE AS INTERMEDIATES TO ANTIMYCOTIC AGENTS | SSP CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| US-6194592-B1 | AS ANTIMYCOTIC AGENT | SSP CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |
| US-6083968-A | A FUNGICIDE; 1,1-DIFLUORO-1-ETHYL THIENYL OR ETHYL THIENYL OXIDES-2-(2,4-SUBSTITUTED PHENYL)-3-(1H-1,2,4-TRIA ZOL-1-YL)-2-OXY OR HYDROXY COMPOUND | SSP CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0927719-A1 | Triazole derivative or salt thereof, preparation process thereof as well as pharmaceutical containing said compound | SSP Co., Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |
| EP-0047923-B1 | ISOQUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-05-09 | — | — | EP | disclosed |