SCHEMBL1326535

SCHEMBL1326535

C=C(C(=O)OCCN)C(C)(C)C.C=C(C)C(=O)OC.C=C(CC)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
THRB P10828 1/20 0.35
TSHR P16473 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8442139 0.89 TET2 (0.32) THRB
SCHEMBL1783415 0.89 ALDH1A1 (0.48) ALDH1A1THRBTSHR
Hydrochloric Acid SCHEMBL8440810 0.88 ALDH1A1 (0.47) ALDH1A1THRBTSHR
Acrylic Acid Ethyl Ester SCHEMBL14841853 0.80 ALDH1A1 (0.37) ALDH1A1THRBTSHR
SCHEMBL667786 0.78 ALDH1A1 (0.62) ALDH1A1THRBTSHR
SCHEMBL534164 0.78 THRB (0.34) ALDH1A1THRBTSHR
Chloromethane SCHEMBL5914760 0.77 THRB (0.33) ALDH1A1THRBTSHR
Hydrochloric Acid SCHEMBL590980 0.77 THRB (0.33) ALDH1A1THRBTSHR
SCHEMBL11101921 0.77 ALDH1A1 (0.60) ALDH1A1THRBTSHR
Methacrylic Acid SCHEMBL6333244 0.77 ALDH1A1 (0.60) ALDH1A1THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2061437-B1 COMBINED PHARMACEUTICAL FORMULATION WITH CONTROLLED-RELEASE COMPRISING DIHYDROPYRIDINE CALCIUM CHANNEL BLOCKERS AND HMG-COA REDUCTASE INHIBITORS HANALL BIOPHARMA CO LTD (KR) 2013-10-30 EP claimed
EP-2061437-A1 COMBINED PHARMACEUTICAL FORMULATION WITH CONTROLLED-RELEASE COMPRISING DIHYDROPYRIDINE CALCIUM CHANNEL BLOCKERS AND HMG-COA REDUCTASE INHIBITORS Hanall Pharmaceutical Co., Ltd. (KR) 2009-05-27 EP claimed
US-20080241240-A1 COMBINED PHARMACEUTICAL FORMULATION WITH CONTROLLED-RELEASE COMPRISING DIHYDROPYRIDINE CALCIUM CHANNEL BLOCKERS AND HMG-COA REDUCTASE INHIBITORS HANALL PHARMACEUTICAL CO., LTD. (KR) 2008-10-02 US claimed
WO-2008023869-A1 COMBINED PHARMECEUTICAL FORMULATION WITH CONTROLLED-RELEASE COMPRISING DIHYDROPYRIDINE CALCIUM CHANNEL BLOCKERS AND HMG-COA REDUCTASE INHIBITORS HANALL PHARMACEUTICAL CO., LTD. (KR) 2008-02-28 WO claimed
WO-2008023958-A1 COMBINED PHARMACEUTICAL FORMULATION WITH CONTROLLED-RELEASE COMPRISING DIHYDROPYRIDINE CALCIUM CHANNEL BLOCKERS AND HMG-COA REDUCTASE INHIBITORS HANALL PHARMACEUTICAL CO., LTD. (KR) 2008-02-28 WO claimed
US-20080050432-A1 Combined Pharmaceutical Formulation with Controlled-Release Comprising Dihydropyridine Calcium Channel Blockers and HMG-COA Reductase Inhibitors HANALL BIOPHARMA CO., LTD. (KR) 2008-02-28 US claimed
EP-2109447-B1 N, N- DIMETHYL IMIDODICARBONIMIDIC DIAMIDE ACETATE, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME HANALL BIOPHARMA CO LTD (KR) 2015-06-10 EP disclosed
EP-2061437-B1 COMBINED PHARMACEUTICAL FORMULATION WITH CONTROLLED-RELEASE COMPRISING DIHYDROPYRIDINE CALCIUM CHANNEL BLOCKERS AND HMG-COA REDUCTASE INHIBITORS HANALL BIOPHARMA CO LTD (KR) 2013-10-30 EP disclosed
US-8541474-B2 N,N-dimethyl imidodicarbonimidic diamide acetate, method for producing the same and pharmaceutical compositions comprising the same HANALL BIOPHARMA CO., LTD. (KR) 2013-09-24 US disclosed
US-20120010287-A1 N, N -DIMETHYL IMIDODICARBONIMIDIC DIAMIDE ACETATE, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME HANNAL BIOPHARMA CO., LTD. (KR) 2012-01-12 US disclosed
US-8058312-B2 N, N-dimethyl imidodicarbonimidic diamide acetate, method for producing the same and pharmaceutical compositions comprising the same HANALL BIOPHARMA CO., LTD. (KR) 2011-11-15 US disclosed
US-20100087544-A1 N, N -DIMETHYL IMIDODICARBONIMIDIC DIAMIDE ACETATE, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME HANALL PHARMACEUTICAL COMPANY, LTD. (KR) 2010-04-08 US disclosed
EP-2109447-A1 N, N- DIMETHYL IMIDODICARBONIMIDIC DIAMIDE ACETATE, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME Hanall Pharmaceutical Company LTD. (KR) 2009-10-21 EP disclosed
EP-2061437-A1 COMBINED PHARMACEUTICAL FORMULATION WITH CONTROLLED-RELEASE COMPRISING DIHYDROPYRIDINE CALCIUM CHANNEL BLOCKERS AND HMG-COA REDUCTASE INHIBITORS Hanall Pharmaceutical Co., Ltd. (KR) 2009-05-27 EP disclosed
US-20080241240-A1 COMBINED PHARMACEUTICAL FORMULATION WITH CONTROLLED-RELEASE COMPRISING DIHYDROPYRIDINE CALCIUM CHANNEL BLOCKERS AND HMG-COA REDUCTASE INHIBITORS HANALL PHARMACEUTICAL CO., LTD. (KR) 2008-10-02 US disclosed
WO-2008093984-A1 N, N- DIMETHYL IMIDODICARBONIMIDIC DIAMIDE ACETATE, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME HANALL PHARMACEUTICAL COMPANY. LTD (KR) 2008-08-07 WO disclosed
WO-2008023869-A1 COMBINED PHARMECEUTICAL FORMULATION WITH CONTROLLED-RELEASE COMPRISING DIHYDROPYRIDINE CALCIUM CHANNEL BLOCKERS AND HMG-COA REDUCTASE INHIBITORS HANALL PHARMACEUTICAL CO., LTD. (KR) 2008-02-28 WO disclosed
WO-2008023958-A1 COMBINED PHARMACEUTICAL FORMULATION WITH CONTROLLED-RELEASE COMPRISING DIHYDROPYRIDINE CALCIUM CHANNEL BLOCKERS AND HMG-COA REDUCTASE INHIBITORS HANALL PHARMACEUTICAL CO., LTD. (KR) 2008-02-28 WO disclosed
US-20080050432-A1 Combined Pharmaceutical Formulation with Controlled-Release Comprising Dihydropyridine Calcium Channel Blockers and HMG-COA Reductase Inhibitors HANALL BIOPHARMA CO., LTD. (KR) 2008-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087544-A1 N, N -DIMETHYL IMIDODICARBONIMIDIC DIAMIDE ACETATE, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME TP53, TNNC1, TNNI3 ALDH1A1 1197/4885THRB 3070/4885TSHR 3686/4885
US-20120010287-A1 N, N -DIMETHYL IMIDODICARBONIMIDIC DIAMIDE ACETATE, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME TP53, TNNC1, TNNI3 ALDH1A1 1197/4885THRB 3070/4885TSHR 3686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.