Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | SCD | O00767 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634461 | 0.86 | PTPN1 (0.70) | MEN1KMT2AALDH1A1FSCN1PTPN1 | |
| SCHEMBL13265852 | 0.82 | MEN1 (0.65) | MEN1KMT2AALDH1A1FSCN1PTPN1 | |
| SCHEMBL13265860 | 0.79 | FBP1 (0.57) | MEN1KMT2AALDH1A1PTPN1NPC1 | |
| SCHEMBL13265929 | 0.77 | MEN1 (0.62) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13265865 | 0.76 | ALDH1A1 (0.70) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL617744 | 0.74 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1PKMNPC1 | |
| SCHEMBL13265926 | 0.74 | CA2 (0.51) | MEN1KMT2AALDH1A1FSCN1PKM | |
| SCHEMBL13265923 | 0.74 | KMT2A (0.56) | MEN1KMT2AALDH1A1PKMCYP3A4 | |
| SCHEMBL13265868 | 0.74 | KMT2A (0.64) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL15521858 | 0.74 | FSCN1 (1.00) | MEN1KMT2AALDH1A1FSCN1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754773-B2 | Composition and synthesis of new reagents for inhibition of HIV replication | UNIVERSITY OF MASSACHUSETTS (US) | 2010-07-13 | — | — | US | disclosed |