Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ENO1 | P06733 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836561 | 0.82 | MEN1 (0.37) | LMNATSHRMEN1HPGDBLM | |
| SCHEMBL19347004 | 0.82 | MEN1 (0.37) | LMNATSHRMEN1HPGDBLM | |
| SCHEMBL15257435 | 0.80 | LMNA (0.38) | LMNATSHRTDP1CYP2D6ALDH1A1 | |
| SCHEMBL5961220 | 0.80 | LAP3 (0.37) | LMNATSHRMEN1HPGDBLM | |
| SCHEMBL3283984 | 0.77 | LAP3 (0.38) | LMNATSHRMEN1HPGDBLM | |
| SCHEMBL29170733 | 0.77 | LMNA (0.39) | LMNATSHRCYP2D6ALDH1A1MAPT | |
| SCHEMBL21122548 | 0.77 | LMNA (0.39) | LMNATSHRCYP2D6ALDH1A1MAPT | |
| SCHEMBL8715424 | 0.77 | LMNA (0.39) | LMNATSHRTDP1CYP2D6ALDH1A1 | |
| Phosphoric Acid SCHEMBL31116634 | 0.76 | LMNA (0.47) | LMNATSHRMEN1KMT2ACYP2D6 | |
| SCHEMBL7514477 | 0.76 | MEN1 (0.36) | LMNATSHRMEN1HPGDBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447355-A | Preparation method of milbelin intermediate | 南京威凯尔生物医药科技有限公司 | 2024-01-26 | — | — | CN | claimed |
| US-8058475-B2 | Substituted cyclohexylmethyl compounds | GRUENENTHAL GMBH (DE) | 2011-11-15 | — | — | US | claimed |
| EP-1989174-B1 | SUBSTITUTED CYCLOHEXYLMETHYL DERIVATIVES | GRUENENTHAL GMBH (DE) | 2011-08-03 | — | — | EP | claimed |
| US-20090286833-A1 | Substituted Cyclohexylmethyl Compounds | GRUENENTHAL GMBH (DE) | 2009-11-19 | — | — | US | claimed |
| EP-1038900-B1 | Double metal cyanide catalysts for the production of polyetherpolyols | BAYER MATERIALSCIENCE AG (DE) | 2004-07-14 | — | — | EP | claimed |
| US-6468939-B1 | ESTERS OF PHOSPHORIC ACID, PHOSPHOROUS ACID, PHOSPHONIC ACID, PHOSPHONOUS ACID, PHOSPHINIC ACID OR PHOSPHINOUS ACID; COMPLEXING LIGANDS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | claimed |
| CN-115819216-A | Preparation method of 10-hydroxy-2-decenoic acid | 昆明博鸿科技有限公司 | 2023-03-21 | — | — | CN | disclosed |
| US-9908819-B1 | Printing method for production a ceramic green body | WZR ceramic solutions GmbH (DE) | 2018-03-06 | — | — | US | disclosed |
| US-20160297829-A1 | METHOD FOR PRODUCING AVENACIOLIDES AND USES THEREOF | ACADEMIA SINICA (TW) | 2016-10-13 | — | — | US | disclosed |
| CN-105829305-A | NRF2 REGULATORS | 葛兰素史密斯克莱知识产权发展有限公司 | 2016-08-03 | — | — | CN | disclosed |
| US-8901333-B2 | Nanocrystals with functional ligands | Life Technologies Corporation (US) | 2014-12-02 | — | — | US | disclosed |
| US-8324222-B2 | Cyclically substituted furopyrimidine derivatives and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-12-04 | — | — | US | disclosed |
| US-8058475-B2 | Substituted cyclohexylmethyl compounds | GRUENENTHAL GMBH (DE) | 2011-11-15 | — | — | US | disclosed |
| US-4931591-A | Novel 5-amino-4-hydroxyvaleryl derivatives | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| US-4727060-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| US-4570648-A | Flavorants containing esters of 2,3,6,6-tetramethylcyclohexenyl carboxylic acids | GIVAUDAN CORPORATION (US) | 1986-02-18 | — | — | US | disclosed |
| US-4497830-A | Carbacyclins, their preparation and pharmacological use | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-02-05 | — | — | US | disclosed |
| US-4474687-A | PERFUMES, FLAYORS | GIVAUDAN CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |
| US-4375001-A | ORGANOLEPTIC AGENT | GIVAUDAN CORPORATION | 1983-02-22 | — | — | US | disclosed |
| US-4133817-A | 11-Oxa-prostaglandin analogs | CHEMBRO HOLDINGS (PROPRIETARY) LIMITED (ZA) | 1979-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160297829-A1 | METHOD FOR PRODUCING AVENACIOLIDES AND USES THEREOF | COASY, ERG28, GSK3B | LMNA 3114/4885TSHR 3168/4885MEN1 3715/4885 |
| US-20090286833-A1 | Substituted Cyclohexylmethyl Compounds | CNR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, C1R | LMNA 1432/4885TSHR 760/4885MEN1 1779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.