Catechol

Catechol

SCHEMBL132726

OBO.Oc1ccccc1O

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.77
CA2 P00918 6/20 0.77
HPGD P15428 4/20 0.77
TDP1 Q9NUW8 4/20 0.77
CA4 P22748 4/20 0.77
ALOX15 P16050 3/20 0.77
LMNA P02545 3/20 0.77
HSD17B10 Q99714 3/20 0.77
KDM4E B2RXH2 3/20 0.77
SMN1; SMN2 Q16637 3/20 0.77
CA12 O43570 3/20 0.77
CA14 Q9ULX7 3/20 0.77
EGFR P00533 2/20 0.77
FYN P06241 2/20 0.77
MMP9 P14780 2/20 0.77
RECQL P46063 2/20 0.77
NPC1 O15118 2/20 0.77
MAPT P10636 2/20 0.77
CA3 P07451 2/20 0.77
GMNN O75496 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Catechol SCHEMBL28985421 1.00 ALDH1A1 (0.77) ALDH1A1CA2HPGDTDP1CA4
Catechol SCHEMBL11672589 0.88 ALDH1A1 (1.00) ALDH1A1CA2HPGDTDP1CA4
Catechol SCHEMBL29352716 0.88
Catechol SCHEMBL30088487 0.88
Catechol SCHEMBL367675 0.88 ALDH1A1 (1.00) ALDH1A1CA2HPGDTDP1CA4
Catechol SCHEMBL18351 0.88
Catechol SCHEMBL30944695 0.88 ALDH1A1 (1.00) ALDH1A1CA2HPGDTDP1CA4
Catechol SCHEMBL25313512 0.84
Catechol SCHEMBL5706397 0.84 ALDH1A1 (0.91) ALDH1A1CA2HPGDTDP1CA4
Catechol SCHEMBL16393831 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240408272-A1 BIO-ABSORBABLE DISPERSIBLE RAPIDLY DEPLOYABLE WOUND INTERFACE KCI MANUFACTURING UNLIMITED COMPANY (IE) 2024-12-12 US claimed
CN-118994216-A 2-Boron ester-norbornene and use thereof and polymer containing alkenyl boron ester in main chain 北京大学 2024-11-22 CN claimed
WO-2022234444-A1 BIO-ABSORBABLE DISPERSIBLE RAPIDLY DEPLOYABLE WOUND INTERFACE KCI MANUFACTURING UNLIMITED COMPANY (IE) 2022-11-10 WO claimed
US-20240408272-A1 BIO-ABSORBABLE DISPERSIBLE RAPIDLY DEPLOYABLE WOUND INTERFACE KCI MANUFACTURING UNLIMITED COMPANY (IE) 2024-12-12 US disclosed
US-11814393-B2 Substituted guanidine compounds UBE CORPORATION (JP) 2023-11-14 US disclosed
CN-115417999-B One-dimensional polyrotaxane constructed based on coordination boron-nitrogen bond, and preparation method and application thereof 浙江大学杭州国际科创中心 2023-07-07 CN disclosed
WO-2022249992-A1 PRODUCTION METHOD FOR BIPYRIDINE DERIVATIVE, PRODUCTION METHOD FOR MACROCYCLIC COMPOUND, PRODUCTION METHOD FOR METAL COMPLEX INCLUDING MACROCYCLIC COMPOUND AS LIGAND, METAL COMPLEX, ELECTRODE FOR AIR BATTERY, AND AIR BATTERY 住友化学株式会社 2022-12-01 WO disclosed
WO-2022234444-A1 BIO-ABSORBABLE DISPERSIBLE RAPIDLY DEPLOYABLE WOUND INTERFACE KCI MANUFACTURING UNLIMITED COMPANY (IE) 2022-11-10 WO disclosed
US-20220315599-A1 SUBSTITUTED GUANIDINE COMPOUNDS UBE CORP (JP) 2022-10-06 US disclosed
US-11396514-B2 Substituted guanidine compounds UBE CORPORATION 2022-07-26 US disclosed
EP-3564230-B1 SUBSTITUTED GUANIDINE COMPOUND UBE INDUSTRIES (JP) 2022-02-09 EP disclosed
US-6884482-B2 Fuel container having excellent gasoline barrier properties KURARAY CO., LTD. (JP) 2005-04-26 US disclosed
US-20040220366-A1 Block copolymer and thermoplastic resin composition KURARAY CO., LTD. (JP) 2004-11-04 US disclosed
US-20040076780-A1 Method of producing a shaped article having excellent barrier properties KURARAY CO. LTD (JP) 2004-04-22 US disclosed
EP-1369438-A1 BLOCK COPOLYMER AND THERMOPLASTIC RESIN COMPOSITION Kuraray Co., Ltd., Kurashiki Plant (JP) 2003-12-10 EP disclosed
US-20030004165-A1 Polyazanaphthalene compounds and pharmaceutical use thereof AJINOMOTO CO. INC (JP) 2003-01-02 US disclosed
US-20020176955-A1 Fuel container having excellent gasoline barrier properties EVAL COMPANY OF AMERICA 2002-11-28 US disclosed
US-20020172788-A1 Method of producing a shaped article having excellent barrier properties KURARAY CO., LTD. (JP) 2002-11-21 US disclosed
EP-1245381-A1 Fuel container having excellent gasoline barrier properties Kuraray Co., Ltd. (JP) 2002-10-02 EP disclosed
EP-1166892-A2 A method of producing a shaped article having excellent barrier properties Kuraray Co., Ltd. (JP) 2002-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030004165-A1 Polyazanaphthalene compounds and pharmaceutical use thereof MMP1, TNF, MMP12 ALDH1A1 998/4885CA2 963/4885HPGD 115/4885
US-20220315599-A1 SUBSTITUTED GUANIDINE COMPOUNDS GMPS, PDE3B, GUCY1A2 ALDH1A1 557/4885CA2 1116/4885HPGD 924/4885
US-11814393-B2 Substituted guanidine compounds GMPS, PDE3B, GUCY1A2 ALDH1A1 557/4885CA2 1116/4885HPGD 924/4885
US-11396514-B2 Substituted guanidine compounds GMPS, PDE3B, GUCY1A2 ALDH1A1 557/4885CA2 1116/4885HPGD 924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.