Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22635716 | 0.89 | TSHR (0.38) | HSD17B10LMNACYP3A4TSHRALDH1A1 | |
| Acenaphthene SCHEMBL9017 | 0.75 | TSHR (0.57) | HSD17B10LMNACYP3A4TSHRALDH1A1 | |
| Acenaphthene SCHEMBL29386207 | 0.75 | TSHR (0.57) | HSD17B10LMNACYP3A4TSHRALDH1A1 | |
| Acenaphthene SCHEMBL1162573 | 0.75 | TSHR (0.57) | HSD17B10LMNACYP3A4TSHRALDH1A1 | |
| Acenaphthene SCHEMBL28028969 | 0.75 | TSHR (0.57) | HSD17B10LMNACYP3A4TSHRALDH1A1 | |
| Acenaphthene SCHEMBL3416108 | 0.75 | TSHR (0.57) | HSD17B10LMNACYP3A4TSHRALDH1A1 | |
| Acenaphthene SCHEMBL598252 | 0.75 | TSHR (0.57) | HSD17B10LMNACYP3A4TSHRALDH1A1 | |
| SCHEMBL29706425 | 0.73 | TSHR (0.70) | HSD17B10LMNACYP3A4TSHRALDH1A1 | |
| SCHEMBL154911 | 0.73 | TSHR (0.70) | HSD17B10LMNACYP3A4TSHRALDH1A1 | |
| Acenaphthene SCHEMBL29586283 | 0.73 | TSHR (0.55) | HSD17B10LMNACYP3A4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4379833-A1 | NEGATIVE ELECTRODE, LITHIUM ION SECONDARY BATTERY, AND MANUFACTURING METHOD FOR LITHIUM ION SECONDARY BATTERY | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2024-06-05 | — | — | EP | disclosed |
| CN-118043298-A | (Hetero) aryl-substituted bisphenol compound and thermoplastic resin | 罗伊特化学仪器制造公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-117940399-A | Heteroaryl or aryl substituted bisphenol compounds and thermoplastic resins | 三菱瓦斯化学株式会社 | 2024-04-26 | — | — | CN | disclosed |
| CN-111094223-B | binaphthyl compounds | 罗伊特化学仪器制造公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116348558-A | Inkjet ink for forming an image on a substrate, inkjet printing process and ink set, and aqueous pigment dispersion for forming an inkjet ink | 西康制造有限公司 | 2023-06-27 | — | — | CN | disclosed |
| WO-2023008032-A1 | NEGATIVE ELECTRODE, LITHIUM ION SECONDARY BATTERY, AND MANUFACTURING METHOD FOR LITHIUM ION SECONDARY BATTERY | 信越化学工業株式会社 | 2023-02-02 | — | — | WO | disclosed |
| CN-115103675-A | Compounds for the treatment and prevention of central nervous system disorders | 阿巴克西斯治疗公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-109863155-B | Polycyclic aromatic compound, material for organic element, organic electroluminescent element, display device, and lighting device | 学校法人关西学院 | 2022-09-13 | — | — | CN | disclosed |
| CN-110049990-B | Polycyclic aromatic amino compound, material for organic element, organic electroluminescent element, display device, and lighting device | 学校法人关西学院 | 2022-09-13 | — | — | CN | disclosed |
| CN-114773249-A | Compounds, pharmaceutical compositions and methods for treating inflammatory diseases | 艾匹克治疗公司 | 2022-07-22 | — | — | CN | disclosed |
| EP-1510210-A1 | IMMUNITY-RELATED PROTEIN KINASE INHIBITORS | Institute of Medicinal Molecular Design, Inc. (JP) | 2005-03-02 | — | — | EP | disclosed |
| EP-1510207-A1 | THERAPEUTIC DRUG FOR DIABETES | Institute of Medicinal Molecular Design, Inc. (JP) | 2005-03-02 | — | — | EP | disclosed |
| US-20040259877-A1 | Inhibitors against the production and release of inflammatory cytokines | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2004-12-23 | — | — | US | disclosed |
| CN-1489458-A | Inflammatory cytokine production dissociation inhibitor | ��ʽ����ҽҩ��������о��� | 2004-04-14 | — | — | CN | disclosed |
| EP-1352650-A1 | INHIBITORS AGAINST THE PRODUCTION AND RELEASE OF INFLAMMATORY CYTOKINES | Institute of Medicinal Molecular Design, Inc. (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-5489709-A | REACTING MONO-SUBSTITUTEED CYANAMIDE WITH A SECONDARY AMINE | CAMBRIDGE NEUROSCIENCE, INC. | 1996-02-06 | — | — | US | disclosed |
| EP-0634997-A4 | PREPARATION OF SUBSTITUTED GUANIDINES. | CAMBRIDGE NEUROSCIENCE RES (US) | 1995-04-26 | — | — | EP | disclosed |
| EP-0634997-A1 | PREPARATION OF SUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE RESEARCH, INC. (US) | 1995-01-25 | — | — | EP | disclosed |
| US-5298657-A | From a cyanamide and an amine, Lewis acid catalyst | CAMBRIDGE NEUROSCIENCE INC. (US) | 1994-03-29 | — | — | US | disclosed |
| WO-1993019042-A1 | PREPARATION OF SUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1993-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259877-A1 | Inhibitors against the production and release of inflammatory cytokines | NFKBIA, IL1B, IKBKB | HSD17B10 704/4885LMNA 2842/4885CYP3A4 1988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.