Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 6/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13278587 | 0.75 | CSF1R (0.47) | CSF1RKIT | |
| SCHEMBL4848346 | 0.75 | ALDH1A1 (0.42) | SMN1; SMN2HSD17B10MEN1CYP2C19MPO | |
| SCHEMBL13281433 | 0.71 | CSF1R (0.36) | CSF1RSMN1; SMN2HSD17B10MEN1KIT | |
| SCHEMBL5652915 | 0.69 | CSF1R (0.59) | CSF1RKIT | |
| SCHEMBL5210190 | 0.69 | CA12 (0.39) | SMN1; SMN2MEN1 | |
| SCHEMBL26835272 | 0.68 | ICMT (0.47) | PLA2G10PLA2G2AMTNR1ASMN1; SMN2 | |
| SCHEMBL32670782 | 0.68 | POLB (0.64) | PLA2G10PLA2G2AMTNR1AHSD17B10 | |
| SCHEMBL30522046 | 0.68 | KMT2A (0.56) | PLA2G10PLA2G2ASMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL3456256 | 0.68 | KMT2A (0.56) | PLA2G10PLA2G2ASMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL26824456 | 0.68 | PLA2G2A (0.48) | PLA2G10PLA2G2AMTNR1AHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697207-A2 | CYCLOALKENYL ARYL DERIVATIVES FOR CETP INHIBITOR | Chong Kun Dang Pharmaceutical Corp. (KR) | 2014-02-19 | — | — | EP | disclosed |
| WO-2012141487-A2 | CYCLOALKENYL ARYL DERIVATIVES FOR CETP INHIBITOR | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2012-10-18 | — | — | WO | disclosed |