SCHEMBL1328006

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1327676	0.87	CHRM4 (0.42)	ALDH1A1TMEM97SIGMAR1NPC1RAB9A
	SCHEMBL1327941	0.86	RAB9A (0.49)	CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1
	SCHEMBL2311720	0.86	MAPK14 (0.43)	PLK1TMEM97SIGMAR1MEN1KMT2A
	SCHEMBL1327451	0.81	L3MBTL1 (0.42)	CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1
	SCHEMBL1327804	0.78	SMYD3 (0.53)	ALDH1A1LMNAMEN1KMT2ANPC1
	SCHEMBL1326720	0.78	LMNA (0.57)	ALDH1A1LMNASIGMAR1MEN1KMT2A
	SCHEMBL494017	0.78	RAB9A (0.41)	CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL8337991	0.78	PLK1 (0.62)	PLK1CYP1A2CYP2C19ALDH1A1LMNA
	SCHEMBL1327306	0.77	MEN1 (0.48)	ALDH1A1LMNAMEN1KMT2ANPC1
	SCHEMBL1328137	0.77	MCHR1 (0.50)	NPSR1ALDH1A1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.