SCHEMBL13281114

SCHEMBL13281114

O=[N+]([O-])c1cn(CC[C@@H](O)CO)c(Cl)n1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
KMT2A Q03164 2/20 0.39
PKM P14618 2/20 0.37
SOS1 Q07889 1/20 0.36
MITF O75030 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.33
POLB P06746 1/20 0.32
CHRM1 P11229 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13280994 1.00 ALDH1A1 (0.40) ALDH1A1KMT2APKMSOS1MITF
SCHEMBL15442198 1.00 ALDH1A1 (0.40) ALDH1A1KMT2APKMSOS1MITF
SCHEMBL14004051 0.88 ALDH1A1 (0.46) ALDH1A1KMT2APKMSOS1MITF
SCHEMBL28523274 0.86 ALDH1A1 (0.42) ALDH1A1KMT2APKMSOS1MITF
SCHEMBL28523272 0.86 ALDH1A1 (0.42) ALDH1A1KMT2APKMSOS1MITF
SCHEMBL1228537 0.83 ALDH1A1 (0.40) ALDH1A1KMT2APKMSOS1MITF
SCHEMBL14004043 0.83 ALDH1A1 (0.42) ALDH1A1KMT2APKMSOS1MITF
SCHEMBL28531344 0.77 CHRM1 (0.47) ALDH1A1KMT2APKMSOS1MITF
SCHEMBL5539609 0.77 CHRM1 (0.47) ALDH1A1KMT2APKMSOS1MITF
SCHEMBL1228814 0.76 KMT2A (0.33) ALDH1A1KMT2APKMSOS1MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2697232-B1 6,7-DIHYDROIMIDAZO[2,1-B][1,3]OXAZINE BACTERICIDES OTSUKA PHARMA CO LTD (JP) 2016-05-18 EP disclosed
US-9051333-B2 6,7-dihydroimidazo [2,1-b] [1,3]oxazine bactericides OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2015-06-09 US disclosed
EP-2697232-A1 6,7 - DIHYDROIMIDAZO [2, 1 - B][1, 3]OXAZINE BACTERICIDES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2014-02-19 EP disclosed
US-20140031342-A1 6,7-DIHYDROIMIDAZO [2,1-b] [1,3]OXAZINE BACTERICIDES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2014-01-30 US disclosed
WO-2012141338-A1 6,7 - DIHYDROIMIDAZO [2, 1 - B] [1, 3] OXAZINE BACTERICIDES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2012-10-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140031342-A1 6,7-DIHYDROIMIDAZO [2,1-b] [1,3]OXAZINE BACTERICIDES BRD1, OXA1L, QDPR ALDH1A1 109/4885KMT2A 3220/4885PKM 3051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.