Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2878933 | 1.00 | APLNR (0.34) | APLNRTSHRKMT2ASLC1A2SLC1A1 | |
| SCHEMBL13260297 | 1.00 | APLNR (0.34) | APLNRTSHRKMT2ASLC1A2SLC1A1 | |
| SCHEMBL13260298 | 0.83 | ALDH1A1 (0.30) | — | |
| SCHEMBL13260299 | 0.83 | ALDH1A1 (0.30) | — | |
| SCHEMBL2876689 | 0.83 | ALDH1A1 (0.30) | — | |
| SCHEMBL21103462 | 0.79 | — | — | |
| SCHEMBL6173752 | 0.76 | APLNR (0.52) | APLNRTSHRKMT2A | |
| SCHEMBL21103066 | 0.75 | — | — | |
| SCHEMBL7026682 | 0.75 | TSHR (0.41) | TSHRKMT2A | |
| SCHEMBL21103067 | 0.74 | EPHX2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010083207-A2 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | RIGEL PHARMACEUTICALS, INC. (US) | 2010-07-22 | — | — | WO | disclosed |