SCHEMBL6173752

SCHEMBL6173752

CON1C(C)(C)CC(C(=O)O)CC1(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.52
CYP2C19 P33261 2/20 0.44
CYP1A2 P05177 2/20 0.39
ALOX15 P16050 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TSHR P16473 3/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.32
GRM2 Q14416 2/20 0.31
GRM3 Q14832 2/20 0.31
GRM4 Q14833 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
GRM8 O00222 1/20 0.31
GRM6 O15303 1/20 0.31
LMNA P02545 1/20 0.31
GRM5 P41594 1/20 0.31
MTOR P42345 1/20 0.31
GRM1 Q13255 1/20 0.31
PLCB1 Q9NQ66 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17586729 0.87 TSHR (0.41) APLNRCYP2C19CYP1A2ALOX15TSHR
SCHEMBL17586683 0.82 TSHR (0.33) APLNRALDH1A1TSHRKMT2A
SCHEMBL17586731 0.80 APLNR (0.39) APLNRCYP2C19CYP1A2ALOX15KDM4E
SCHEMBL14409846 0.79
SCHEMBL15732386 0.77 TSHR (0.31) ALDH1A1TSHRKMT2A
SCHEMBL13260297 0.76 APLNR (0.34) APLNRTSHRKMT2A
SCHEMBL13282247 0.76 APLNR (0.34) APLNRTSHRKMT2A
SCHEMBL2878933 0.76 APLNR (0.34) APLNRTSHRKMT2A
SCHEMBL21163426 0.76 TSHR (0.33) ALDH1A1TSHRKMT2A
SCHEMBL21879738 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6875870-B2 Long chain hindered amines and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-04-05 US claimed
EP-1379587-B1 LONG CHAIN HINDERED AMINES AND COMPOSITIONS STABILIZED THEREWITH CIBA SC HOLDING AG (CH) 2005-02-02 EP claimed
US-20040138452-A1 Long chain hindered amines and compositions stabilized therewith WOOD MERVIN G (US) 2004-07-15 US claimed
EP-1379587-A1 LONG CHAIN HINDERED AMINES AND COMPOSITIONS STABILIZED THEREWITH Ciba SC Holding AG (CH) 2004-01-14 EP claimed
US-20030125555-A1 Long chain hindered amines and compositions stabilized therewith WOOD MERVIN G (US) 2003-07-03 US claimed
US-20030109704-A1 Long chain hindered amines and compositions stabilized therewith WOOD MERVIN G (US) 2003-06-12 US claimed
WO-2002083781-A1 LONG CHAIN HINDERED AMINES AND COMPOSITIONS STABILIZED THEREWITH CIBA SPECIALTY CHEMICALS HOLDING INC. (US) 2002-10-24 WO claimed
US-10663864-B2 Pattern forming method, method for manufacturing electronic device, and laminate FUJIFILM CORPORATION (JP) 2020-05-26 US disclosed
US-20180181003-A1 PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND LAMINATE FUJIFILM CORPORATION (JP) 2018-06-28 US disclosed
US-20180181003-A1 PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND LAMINATE FUJIFILM CORPORATION (JP) 2018-06-28 US disclosed
US-9738657-B2 Highly efficient polarizing agents for dynamic nuclear polarization Bruker BioSpin S.A.S. (FR) 2017-08-22 US disclosed
US-20160075732-A1 RADICAL ORBITAL SWITCHING THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2016-03-17 US disclosed
US-20160075732-A1 RADICAL ORBITAL SWITCHING THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2016-03-17 US disclosed
US-6755875-B2 PIPERIDINE-N-OXY GROUP CONTAINING COMPOUNDS STABILIZES WHITE, DYED, DIPPED, UNSCENTED OR SCENTED CANDLE WAX AGAINST DISCOLRATION AND FADING CIBA SPECIALTY CHEMICALS CORPORATION 2004-06-29 US disclosed
US-6699298-B2 DISCOLORATION INHIBITION CANDLE WAX CIBA SPECIALTY CHEMICALS CORPORATION 2004-03-02 US disclosed
EP-1379587-A1 LONG CHAIN HINDERED AMINES AND COMPOSITIONS STABILIZED THEREWITH Ciba SC Holding AG (CH) 2004-01-14 EP disclosed
US-20030125555-A1 Long chain hindered amines and compositions stabilized therewith WOOD MERVIN G (US) 2003-07-03 US disclosed
US-20030109704-A1 Long chain hindered amines and compositions stabilized therewith WOOD MERVIN G (US) 2003-06-12 US disclosed
WO-2002083781-A1 LONG CHAIN HINDERED AMINES AND COMPOSITIONS STABILIZED THEREWITH CIBA SPECIALTY CHEMICALS HOLDING INC. (US) 2002-10-24 WO disclosed
US-6465645-B1 CONTAINING TRIAZINE GROUPS AND N-ALKYLOXYPIPERIDINE GROUPS; CANDLE WAX WHICH IS EFFECTIVELY STABILIZED AGAINST DISCOLORATION AND FADING CIBA SPECIALTY CHEMICALS CORPORATION 2002-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109704-A1 Long chain hindered amines and compositions stabilized therewith TYR, DDC, AOC2 APLNR 3327/4885CYP2C19 1021/4885CYP1A2 723/4885
US-20030125555-A1 Long chain hindered amines and compositions stabilized therewith TYR, DDC, AOC2 APLNR 3327/4885CYP2C19 1021/4885CYP1A2 723/4885
US-20040138452-A1 Long chain hindered amines and compositions stabilized therewith TYR, DDC, AOC2 APLNR 3327/4885CYP2C19 1021/4885CYP1A2 723/4885
US-20160075732-A1 RADICAL ORBITAL SWITCHING RAD1, RAD54L, NQO1 APLNR 1604/4885CYP2C19 984/4885CYP1A2 1710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.