Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 4/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378668 | 0.88 | NPSR1 (0.45) | ALDH1A1LMNANPSR1HTTRAB9A | |
| SCHEMBL13282987 | 0.86 | ALDH1A1 (0.57) | ALDH1A1LMNACACNA1GCACNA1HCACNA1I | |
| SCHEMBL13102403 | 0.84 | TRPV4 (0.43) | TRPV4ALDH1A1LMNACACNA1GCACNA1H | |
| SCHEMBL13282996 | 0.82 | HTT (0.44) | ALDH1A1LMNANPSR1HTTRAB9A | |
| SCHEMBL13283034 | 0.79 | NPSR1 (0.48) | ALDH1A1LMNANPSR1HTTRAB9A | |
| SCHEMBL13283153 | 0.79 | NPSR1 (0.52) | ALDH1A1LMNACACNA1GCACNA1HCACNA1I | |
| SCHEMBL13282920 | 0.78 | NPSR1 (0.53) | ALDH1A1LMNAP2RY14NPSR1HTT | |
| SCHEMBL13282879 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNANPSR1HTTRAB9A | |
| SCHEMBL13283005 | 0.77 | RAB9A (0.45) | ALDH1A1LMNANPSR1HTTRAB9A | |
| SCHEMBL13282994 | 0.77 | NPSR1 (0.59) | ALDH1A1LMNACACNA1GCACNA1HCACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190746-A1 | QUINAZOLINONES AS POTASSIUM CHANNEL MODULATORS | ICAGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190746-A1 | QUINAZOLINONES AS POTASSIUM CHANNEL MODULATORS | KCNQ1, KCNK17, KCNQ2 | TRPV4 175/4885ALDH1A1 2776/4885LMNA 1144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.