SCHEMBL1328352

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2308758	0.90	TSHR (0.47)	TSHRSMN1; SMN2
	SCHEMBL1326310	0.89	OPRL1 (0.48)	SMN1; SMN2ALDH1A1POLBKCNQ2
	Hydrochloric Acid SCHEMBL1327186	0.89	TSHR (0.46)	TSHRSMN1; SMN2
	SCHEMBL13114604	0.87	ALDH1A1 (0.54)	SMN1; SMN2ALDH1A1POLBCRHBPCRHR2
	SCHEMBL1327847	0.83	POLB (0.47)	SMN1; SMN2ALDH1A1POLBCRHBPCRHR2
	SCHEMBL28810401	0.82	TSHR (0.48)	TSHRLMNA
	Cyclopentane SCHEMBL2306640	0.81	TSHR (0.50)	TSHRSMN1; SMN2LMNA
	Cyclohexane SCHEMBL2304945	0.81	TSHR (0.50)	TSHRSMN1; SMN2LMNA
	SCHEMBL578174	0.80	TSHR (0.59)	TSHRSMN1; SMN2LMNA
	SCHEMBL493318	0.80	CYP3A4 (0.47)	TSHRSMN1; SMN2LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.