Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | CCR1 | P32246 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13114604 | 0.92 | ALDH1A1 (0.54) | LMNASMN1; SMN2KMT2A | |
| SCHEMBL27691760 | 0.86 | EPHX1 (0.50) | TSHREPHX1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL10378518 | 0.86 | EPHX1 (0.50) | TSHREPHX1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL10527496 | 0.86 | MAPK1 (0.61) | TSHREPHX1LMNASMN1; SMN2 | |
| SCHEMBL25590428 | 0.84 | ALDH1A1 (0.57) | TSHRCYP3A4CYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL20063945 | 0.81 | EPHX1 (0.54) | EPHX1LMNANPC1KMT2AEPHX2 | |
| SCHEMBL8315751 | 0.81 | KCNQ2 (0.44) | TSHRCYP3A4CYP2C19LMNAHPGD | |
| SCHEMBL18658213 | 0.80 | SIGMAR1 (0.61) | CYP2C19SMN1; SMN2KMT2A | |
| SCHEMBL1328352 | 0.80 | TSHR (0.45) | TSHRLMNASMN1; SMN2 | |
| SCHEMBL15189100 | 0.80 | GRM7 (0.68) | TSHREPHX1CYP3A4CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418190-B1 | The method of preparation of enantiomerically enriched products of condensation from racemic acids or acids of the low enentiomeric purity | POLITECHNIKA LODZKA (PL) | 2013-08-28 | — | — | EP | disclosed |
| EP-2418190-A1 | The method of preparation of enantiomerically enriched products of condensation from racemic acids or acids of the low enentiomeric purity | Politechnika Lodzka (PL) | 2012-02-15 | — | — | EP | disclosed |